PMID: 9172268May 1, 1997Paper

Non-invasive determination of port wine stain anatomy and physiology for optimal laser treatment strategies

Physics in Medicine and Biology
M J van GemertL O Svaasand

Abstract

The treatment of port wine stains (PWSs) using a flashlamp-pumped pulsed dye laser is often performed using virtually identical irradiation parameters. Although encouraging clinical results have been reported, we propose that lasers will only reach their full potential provided treatment parameters match individual PWS anatomy and physiology. The purpose of this paper is to review the progress made on the technical development and clinical implementation of (i) infrared tomography (IRT), optical reflectance spectroscopy (ORS) and optical low-coherence reflectometry (OLCR) to obtain in vivo diagnostic data on individual PWS anatomy and physiology and (ii) models of light and heat propagation, predicting irreversible vascular injury in human skin, to select optimal laser wavelength, pulse duration, spot size and radiant exposure for complete PWS blanching in the fewest possible treatment sessions. Although non-invasive optical sensing techniques may provide significant diagnostic data, development of a realistic model will require a better understanding of relevant mechanisms for irreversible vascular injury.

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Citations

Apr 1, 1999·Lasers in Surgery and Medicine·T J PfeferA J Welch
Mar 1, 2002·Lasers in Surgery and Medicine·John A ViatorJ Stuart Nelson
May 25, 2007·Lasers in Medical Science·Matija MilanicJ Stuart Nelson
Jan 21, 2010·Lasers in Medical Science·Tom ListerPaul Chappell
Oct 22, 2013·Lasers in Medical Science·T ListerP H Chappell
Jan 10, 2003·The Journal of Investigative Dermatology. Symposium Proceedings·Nikiforos Kollias, Georgios N Stamatas
Sep 24, 2004·Annals of Plastic Surgery·Vivek Sivarajan, Iain R MacKay
Jan 20, 2005·The British Journal of Dermatology·S HernP S Mortimer
Sep 3, 2011·Dermatologic Surgery : Official Publication for American Society for Dermatologic Surgery [et Al.]·Haixia QiuNaiyan Huang
Apr 7, 2004·Journal of Biomedical Optics·Bernard ChoiJ Stuart Nelson
Aug 22, 2003·Dermatologic Surgery : Official Publication for American Society for Dermatologic Surgery [et Al.]·Chun-Hung ChiuJ Stuart Nelson
Apr 23, 2002·Dermatologic Surgery : Official Publication for American Society for Dermatologic Surgery [et Al.]·Kristen M KellyJ Stuart Nelson
Feb 26, 1999·Dermatologic Surgery : Official Publication for American Society for Dermatologic Surgery [et Al.]·K V LeI J Frieden
Jan 12, 2010·Journal of Biomedical Optics·Matija Milanic, Boris Majaron
Mar 26, 2016·IEEE Journal of Selected Topics in Quantum Electronics : a Publication of the IEEE Lasers and Electro-optics Society·Bernard ChoiJ Stuart Nelson
Nov 28, 2006·Journal of Plastic, Reconstructive & Aesthetic Surgery : JPRAS·Vivek SivarajanIain R Mackay
Oct 19, 2016·Lasers in Surgery and Medicine·Linzhuang XingGuoxiang Wang
Jan 10, 2008·Physics in Medicine and Biology·Boris Majaron, Matija Milanic
Sep 21, 2005·Archives of Facial Plastic Surgery·Kristen M KellyJ Stuart Nelson

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