Non-invasive diagnosis of in stent stenosis by stress 99m technetium tetrofosmin myocardial perfusion imaging.

The International Journal of Cardiovascular Imaging
Abdou ElhendyDon Poldermans

Abstract

The aim of this study was to assess the accuracy of stress 99m technetium tetrofosmin myocardial perfusion imaging for the diagnosis of in stent stenosis (ISS). We studied 72 patients who underwent exercise or dobutamine stress 99m technetium tetrofosmin imaging, 0.9+/-0.5 years after percutaneous coronary interventions in which stents were deployed. Coronary angiography was performed within 3 months of the stress test. ISS was defined as > or =50% stenosis in a coronary segment with previous stenting. Significant coronary artery disease (CAD) was defined as > or =50% stenosis within or outside the stented coronary segment. The stent was deployed in 1 coronary artery in 52 patients, and in 2 coronary arteries in 20 patients (a total of 92 detected in 42 (58%) patients (51 stents). Reversible perfusion abnormalities were present in 34 of patients with ISS (sensitivity=81%, CI 70-94). Regional sensitivity for diagnosis of stenosis per stent was 76% (CI 65-88), specificity was 83% (CI 71-94) and accuracy was 79% (CI 69-85). Reversible perfusion abnormalities were detected in > or =2 vascular distributions in 15 of 22 patients with multi-vessel CAD and in 5 of 50 patients without (sensitivity for identifying multivessel CAD=68%, CI...Continue Reading

References

Jan 15, 2002·Journal of the American College of Cardiology·Harry C LoweLevon M Khachigian
Jul 10, 2003·Journal of the American College of Cardiology·Michael J ZellwegerMatthias E Pfisterer
Jul 25, 2003·Journal of the American Society of Echocardiography : Official Publication of the American Society of Echocardiography·Jian-Ping BinSanjiv Kaul
Dec 12, 2003·Journal of Nuclear Cardiology : Official Publication of the American Society of Nuclear Cardiology·Abdou ElhendyDon Poldermans

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Citations

May 5, 2009·Scandinavian Cardiovascular Journal : SCJ·Karl AndersenThorarinn Gudnason
Feb 27, 2010·The American Journal of Cardiology·Daniele AndreiniAntonio Luca Bartorelli

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