Non-invasive forced expiratory flow-volume curves to measure lung function in cats

Respiratory Physiology & Neurobiology
Hylton BarkSimon Godfrey

Abstract

Forced expiratory flow-volume curves were performed in 15 cats using the non-invasive thoracic compression techniques developed for use in human infants. Cats breathed through a face mask and pneumotachygraph from which flow and volume were obtained. Thoracic compression was applied from an inflatable bag in a non-expandable jacket surrounding the animal. Bag inflation at end inspiration was initiated by a computer pulse to a pressurized chamber. Processed signals from the pneumotachygraph determined maximum-forced expiratory flow at lung volume equivalent to functional residual capacity (FRC), termed V'maxFRC. Different compression pressures were used, and the highest value from a technically satisfactory flow-volume loop was taken as the result. Mean (+/- 95% CI) V'maxFRC was 422 (369-475) ml/s. Compared with infants of similar weight (V'maxFRC approximately 180 ml/s), cats had a much higher V'maxFRC. Tests repeated another day showed a mean (+/-95% CI) percentage difference between paired tests to be 2.8 (-12.6, +18.3)%. Non-invasive forced expiratory flow-volume measurements can be reliably obtained in sedated cats.

References

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Citations

Nov 26, 2013·The Veterinary Clinics of North America. Small Animal Practice·Julie E Trzil, Carol R Reinero
Nov 26, 2013·The Veterinary Clinics of North America. Small Animal Practice·Anusha Balakrishnan, Lesley G King
Nov 23, 2006·Respiratory Physiology & Neurobiology·Ana EpsteinHylton Bark
Dec 15, 2010·Journal of Feline Medicine and Surgery·Carol R ReineroVamsi P Guntur
Dec 10, 2019·The Veterinary Clinics of North America. Small Animal Practice·Julie E Trzil
Dec 4, 2021·Tierärztliche Praxis. Ausgabe K, Kleintiere/Heimtiere·Hannah Gareis, Bianka Schulz

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