Non-invasively estimated ICP pulse amplitude strongly correlates with outcome after TBI.

Acta Neurochirurgica. Supplement
Karol P BudohoskiMarek Czosnyka

Abstract

An existing monitoring database of brain signal recordings in patients with head injury has been re-evaluated with regard to the accuracy of estimation of non-invasive ICP (nICP) and its components, with a particular interest in the implications for outcome after head injury. Middle cerebral artery blood flow velocity (FV), ICP and arterial blood pressure (ABP) were recorded. Non-invasive ICP (nICP) was calculated using a mathematical model. Other signals analysed included components of ICP (n" indicates non-invasive): ICP pulse amplitude (Amp, nAmp), amplitude of the respiratory component (Resp, nResp), amplitude of slow vasogenic waves of ICP (Slow, nSlow) and index of compensatory reserve (RAP, nRAP). Mean values of analysed signals were compared against each other and between patients who died and survived. The correlation between ICP and nICP was moderately strong, R = 0.51 (95% prediction interval [PI] 17 mm Hg). The components of nICP and ICP were also moderately correlated with each other: the strongest correlation was observed for Resp vs. nResp (r = 0.66), while weaker for Amp vs. nAmp (r = 0.41). Non-invasive pulse amplitude of ICP showed the strongest association with outcome, with the -difference between those who ...Continue Reading

Citations

Jan 13, 2015·Journal of Neurosurgery·Georgios V VarsosMarek Czosnyka
Dec 22, 2016·Neurocritical Care·Danilo CardimPeter Smielewski
Mar 22, 2016·Journal of Neurosurgical Anesthesiology·Chiara RobbaMarek Czosnyka
Mar 10, 2018·Journal of Neurosurgical Anesthesiology·Jeffrey J Pasternak, William L Lanier
Sep 12, 2014·Neurocritical Care·Randall ChesnutUNKNOWN Participants in the International Multidisciplinary Consensus Conference on Multimodality Monitoring
Jun 18, 2016·Current Neurology and Neuroscience Reports·Omar S AkbikHoward Yonas
Jan 25, 2014·The Journal of Trauma and Acute Care Surgery·Sarah B MurthiThomas M Scalea
Jun 25, 2020·Fluids and Barriers of the CNS·Nicolas CanacRobert B Hamilton
Oct 16, 2019·Fluids and Barriers of the CNS·Isabel Martinez-TejadaMorten Andresen

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