Non-ionizing near-infrared radiation transillumination spectroscopy for breast tissue density and assessment of breast cancer risk

Journal of Biomedical Optics
Michelle SimickLothar Lilge

Abstract

There is increasing attention to prevention as a means to reduce cancer incidence. Prevention interventions or therapies in turn rely on risk assessment programs to identify those women most likely to benefit from education and lifestyle changes. These programs are usually based either on interviews to identify ethnic, genetic, and lifestyle factors contributing to risk or on physical examination of the breast. For the latter it has been shown that the parenchymal density pattern observed in X-ray mammography can be used to assess an individual's risk. Extensive areas of dense, glandular tissue that are relatively radio-opaque are associated with higher breast cancer risk, with an odds ratio of 4 to 6 compared with women in whom the breast density is low owing to an abundance of adipose tissue. Near-infrared optical transillumination spectroscopy has been used previously to investigate the physiological properties of breast tissue. In this study, women were recruited who underwent recently X-ray mammography. The tissue density was assessed by a radiologist. The women then underwent optical transillumination spectroscopy, for which an instrument was developed that delivered visible and near-infrared light to the breast. After be...Continue Reading

References

Sep 1, 1990·Physics in Medicine and Biology·V G PetersG L Frank
Jan 1, 1987·Lasers in Surgery and Medicine·A J WelchM J van Gemert
May 1, 1997·Radiology·J W ByngM J Yaffe
Apr 4, 1998·Photochemistry and Photobiology·V QuaresimaM Ferrari
Sep 24, 1999·Journal of the National Cancer Institute·J P CostantinoH S Wieand
Mar 16, 2000·Journal of the National Cancer Institute
Sep 16, 2000·Photochemistry and Photobiology·R CubedduG Valentini
Feb 24, 2001·Journal of the National Cancer Institute·L Fintor
Mar 21, 2002·Nature Reviews. Cancer·Arthur Schatzkin, Mitchell Gail
Sep 10, 2002·Journal of the Optical Society of America. A, Optics, Image Science, and Vision·Jianan Y QuShengming Xiong
Apr 3, 2003·Journal of the National Cancer Institute·Andrew N FreedmanMitchell H Gail

❮ Previous
Next ❯

Citations

Oct 24, 2007·Analytical and Bioanalytical Chemistry·Venkata Radhakrishna KondepatiJuergen Backhaus
May 1, 2007·Breast Cancer Research and Treatment·Daniel Richard LeffAra Darzi
Nov 9, 2006·Journal of Mammary Gland Biology and Neoplasia·Stavros G DemosAmir H Gandjbakhche
Dec 1, 2004·Journal of Biomedical Optics·Subhadra SrinivasanKeith D Paulsen
Feb 12, 2009·Disease Markers·Shwayta KukretiEnrico Gratton
May 30, 2006·Proceedings of the National Academy of Sciences of the United States of America·Ben BrooksbyKeith D Paulsen
Jan 7, 2009·Journal of Biomedical Optics·Kristina M BlackmoreLothar Lilge
May 2, 2009·Journal of Biomedical Optics·Rachel Estelle ThilwindNatallia E Uzunbajakava
Feb 16, 2016·Clinica Chimica Acta; International Journal of Clinical Chemistry·Akikazu Sakudo
Dec 23, 2015·Translational Oncology·Jeon-Hor ChenMin-Ying Su
Jul 3, 2007·Ageing Research Reviews·Wolfgang WuttkeDana Seidlová-Wuttke
Feb 10, 2009·Journal of Food Science·P PallavT H Gan
Feb 6, 2018·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Monique C TourellKonstantin I Momot
Jul 1, 2010·Reports on Progress in Physics·T DurduranA G Yodh
Jan 11, 2013·Biomedical Optics Express·David R BuschArjun G Yodh
Apr 30, 2019·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Tonima S AliKonstantin I Momot
Feb 6, 2018·Journal of Lasers in Medical Sciences·Parinaz MehnatiFarhood Fahima
Oct 20, 2012·Biomedical Optics Express·Paola TaroniRinaldo Cubeddu
Sep 22, 2005·Technology in Cancer Research & Treatment·Subhadra SrinivasanKeith D Paulsen
Feb 9, 2017·Breast Cancer Research : BCR·Lothar LilgeIrene L Andrulis
May 17, 2008·Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology·Kristina M BlackmoreLothar Lilge

❮ Previous
Next ❯

Related Concepts

Related Feeds

Cell Imaging in CNS

Here is the latest research on cell imaging and imaging modalities, including light-sheet microscopy, in the central nervous system.