Non-ketotic hyperosmolar diabetic pre-coma due to pancreatitis in a boy on continuous ambulatory peritoneal dialysis

P J EmderA R Rosenberg


An unusual case of diabetes secondary to acute pancreatitis in a boy with end-stage renal failure receiving continuous ambulatory peritoneal dialysis (CAPD) is described. A hyperglycaemic, hyperosmolar pre-coma developed, aggravated by associated hypercalcaemia. The glucose content of the dialysis fluid contributed to the hyperglycaemia, which settled as the pancreatitis resolved and lower glucose concentration dialysis fluid was used. Our experience suggests that pancreatic dysfunction should be considered where significant hyperglycaemia occurs during peritoneal dialysis.


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Related Concepts

Acute Disease
Diabetes With Coma (Disorder)
Hyperglycemic Hyperosmolar Nonketotic Coma
Insulin B Chain
Kidney Failure, Chronic
Peritoneal Dialysis, Continuous Ambulatory

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