Non-local means denoising of dynamic PET images

PloS One
Joyita DuttaQuanzheng Li

Abstract

Dynamic positron emission tomography (PET), which reveals information about both the spatial distribution and temporal kinetics of a radiotracer, enables quantitative interpretation of PET data. Model-based interpretation of dynamic PET images by means of parametric fitting, however, is often a challenging task due to high levels of noise, thus necessitating a denoising step. The objective of this paper is to develop and characterize a denoising framework for dynamic PET based on non-local means (NLM). NLM denoising computes weighted averages of voxel intensities assigning larger weights to voxels that are similar to a given voxel in terms of their local neighborhoods or patches. We introduce three key modifications to tailor the original NLM framework to dynamic PET. Firstly, we derive similarities from less noisy later time points in a typical PET acquisition to denoise the entire time series. Secondly, we use spatiotemporal patches for robust similarity computation. Finally, we use a spatially varying smoothing parameter based on a local variance approximation over each spatiotemporal patch. To assess the performance of our denoising technique, we performed a realistic simulation on a dynamic digital phantom based on the Dig...Continue Reading

References

Oct 1, 1989·Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism·L FardeC Halldin
Dec 1, 1987·AJR. American Journal of Roentgenology·W D FoleyR E Hendrick
Dec 1, 1987·Physics in Medicine and Biology·R H Huesman, B M Mazoyer
Dec 1, 1985·Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism·C S Patlak, R G Blasberg
Oct 1, 1984·Circulation·S R BergmannB E Sobel
Mar 1, 1983·Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism·C S PatlakJ D Fenstermacher
May 8, 1998·Physics in Medicine and Biology·J QiT H Farquhar
Jun 11, 1999·IEEE Transactions on Medical Imaging·M N WernickM Milosević
Jun 29, 1999·IEEE Transactions on Medical Imaging·J Qi, R M Leahy
Feb 16, 2000·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·H YoungP Price
Oct 6, 2000·IEEE Transactions on Medical Imaging·J Qi, R M Leahy
Aug 14, 2001·American Journal of Physiology. Endocrinology and Metabolism·A BertoldoC Cobelli
Jul 3, 2002·Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology·Fuji YokoiDean F Wong
Dec 17, 2002·European Journal of Nuclear Medicine and Molecular Imaging·Nanette M T FreedmanStephen L Bacharach
May 8, 2004·European Journal of Nuclear Medicine and Molecular Imaging·Finn Børlum KristensenBerit Mørland
Jul 27, 2004·Physics in Medicine and Biology·Yongfeng YangSimon R Cherry
May 1, 1994·Physics in Medicine and Biology·H H BarrettB M Tsui
May 11, 2006·Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism·Rainer HinzPaul M Grasby
May 13, 2006·IEEE Transactions on Medical Imaging·Jinyi Qi, Ronald H Huesman
Jan 18, 2007·Physics in Medicine and Biology·Belma DogdasRichard M Leahy
Feb 14, 2007·Annals of Nuclear Medicine·Hiroshi WatabeMiho Shidahara
Feb 20, 2007·Molecular Imaging and Biology : MIB : the Official Publication of the Academy of Molecular Imaging·Nicolas SalemZhenghong Lee
Mar 16, 2007·Medical Image Computing and Computer-assisted Intervention : MICCAI·Pierrick CoupéChristian Barillot
Jan 1, 1996·IEEE Transactions on Image Processing : a Publication of the IEEE Signal Processing Society·J A Fessler
Jan 1, 1995·IEEE Transactions on Image Processing : a Publication of the IEEE Signal Processing Society·K Lange, J A Fessler
Feb 29, 2008·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Kevin M JohnsonCharles A Mistretta
Apr 9, 2008·IEEE Transactions on Medical Imaging·P CoupeC Barillot
Apr 22, 2008·European Journal of Nuclear Medicine and Molecular Imaging·Constantinos AnagnostopoulosMarcelo F Di Carli
Feb 4, 2009·IEEE Transactions on Medical Imaging·Zheng LiRichard M Leahy
Jul 17, 2009·IEEE Transactions on Medical Imaging·Yaniv GalStuart Crozier
Jul 29, 2009·IEEE Transactions on Image Processing : a Publication of the IEEE Signal Processing Society·Tolga Tasdizen
Nov 11, 2009·IEEE Transactions on Medical Imaging·Jérôme BoulangerJean Salamero
Jun 18, 2010·Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine·Bradley T ChristianCharles A Mistretta
Jun 29, 2010·Medical Image Analysis·François Rousseau, UNKNOWN Alzheimer's Disease Neuroimaging Initiative
Jan 4, 2013·EJNMMI Research·Anu AutioAnne Roivainen
Jul 12, 2013·EJNMMI Research·Wei ShaSung-Cheng Huang
Aug 21, 2013·Physics in Medicine and Biology·Se Young ChunYuni K Dewaraja
Dec 7, 2013·Theranostics·Joyita DuttaQuanzheng Li

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Citations

Jun 20, 2015·Computational and Mathematical Methods in Medicine·SayedMasoud HashemiRichard S C Cobbold
May 18, 2016·IEEE Transactions on Image Processing : a Publication of the IEEE Signal Processing Society· Le An Dinggang Shen
Apr 14, 2016·Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism·Isadora Lopes AlvesMichel Koole
Jul 16, 2019·Physics in Medicine and Biology·Wenzhuo LuChi Liu
Aug 31, 2019·European Journal of Nuclear Medicine and Molecular Imaging·Jianan CuiQuanzheng Li
Jan 20, 2020·Medical Physics·Hossein Arabi, Habib Zaidi
Jan 26, 2016·Physics in Medicine and Biology·Teresa Correia, Simon Arridge
Jun 25, 2016·Journal of X-ray Science and Technology·Yuanyuan GaoWufan Chen
Jun 2, 2017·Physics in Medicine and Biology·Abolfazl MehranianAndrew J Reader
Dec 29, 2017·Physics in Medicine and Biology·Chao SongMichael A King
Sep 19, 2019·World Journal of Gastroenterology : WJG·Ren-Cai LuShao-Bo Wang
Oct 8, 2020·Journal of Biophotonics·Phaneendra K YalavarthyJaya Prakash
Nov 26, 2020·AJR. American Journal of Roentgenology·Masao WatanabeKaori Togashi
Nov 28, 2020·Annals of Nuclear Medicine·Hossein Arabi, Habib Zaidi
Nov 26, 2020·Physics in Medicine and Biology·G I AngelisS R Meikle
Feb 5, 2021·Biomedical Physics & Engineering Express·Akira SanoKumiko Karasawa
Jan 14, 2021·Biomedical Physics & Engineering Express·Mauro Namías, Robert Jeraj
Dec 19, 2020·Physics in Medicine and Biology·Steven R MeikleJoyita Dutta
Jul 22, 2019·Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine·David MinarikElin Trägårdh
Apr 22, 2021·Physics in Medicine and Biology·Xinhui WangHongwei Ye
May 18, 2021·Microscopy and Microanalysis : the Official Journal of Microscopy Society of America, Microbeam Analysis Society, Microscopical Society of Canada·Longhai LiJing Tian
Oct 20, 2021·Physics in Medicine and Biology·Tzu-An SongJoyita Dutta
Dec 3, 2021·PloS One·Shiyao GuoJingxin Zhang

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Methods Mentioned

BETA
imaging technique
PCA

Software Mentioned

NLM
PCA
Patlak
Digimouse
ST
HYPR

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