Non-Mendelian inheritance revealed in a genetic analysis of sexual progeny of Phytophthora cinnamomi with microsatellite markers

Fungal Genetics and Biology : FG & B
M P DobrowolskiPhilip A O'Brien

Abstract

We report the development of four microsatellite loci into genetic markers for the diploid oomycete plant pathogen Phytophthora cinnamomi and that (AC)(n) and (AG)(n) microsatellites are significantly less frequent than in plant and mammal genomes. A minisatellite motif 14 bp long was also discovered. The four microsatellite loci were used to analyze sexual progeny from four separate crosses of P. cinnamomi. A large proportion of non-Mendelian inheritance was observed across all loci in all four crosses, including inheritance of more than two alleles at a locus and noninheritance of alleles from either parent at a locus. The aberrant inheritance is best explained by nondisjunction at meiosis in both the A1 parent and the A2 trisomic parents, resulting in aneuploid progeny. Two loci on the putative trisomic chromosome showed linkage and no loci were linked to mating type. One aneuploid offspring was shown to have lost alleles at two loci following subculture over 4 years, indicating that aneuploid progeny may not be mitotically stable.

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Citations

Jul 17, 2014·PloS One·Ann I LarssonSandra Brooke
Apr 8, 2014·Phytopathology·Amara R DunnChristine D Smart
Dec 4, 2012·Revista iberoamericana de micología·Johanna del Castillo-MúneraSilvia Restrepo
Feb 14, 2012·Trends in Microbiology·Niklaus J GrünwaldSimone Prospero
Jan 29, 2011·Fungal Genetics and Biology : FG & B·Annelies VercauterenKurt Heungens
Oct 15, 2010·Fungal Biology·Boutet XavierChandelier Anne
Jul 31, 2007·Fungal Genetics and Biology : FG & B·Cyril DutechTatiana Giraud
Jul 15, 2005·The Journal of Eukaryotic Microbiology·Wen-Jing ZhangYun-Fen Shen
May 29, 2007·Conservation Biology : the Journal of the Society for Conservation Biology·Jawad AbdelkrimSarah Samadi
Nov 1, 2007·Molecular Plant Pathology·Trevor KoopmanAdéle McLeod
Apr 29, 2006·Ecology Letters·Kimberly A Selkoe, Robert J Toonen
Mar 13, 2009·FEMS Microbiology Letters· Yin-LingKoji Kageyama
Mar 2, 2016·PloS One·Sirjana Devi ShresthaMark Gijzen
Mar 17, 2021·Molecular Plant Pathology·Audrey M V Ah-FongHoward S Judelson

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