Non-neoplastic Pathology in Tumor Nephrectomy Specimens

Surgical Pathology Clinics
Vanesa Bijol, Ibrahim Batal

Abstract

Risk factors for kidney cancers and medical kidney diseases are similar; therefore, it is not surprising that up to 25% of renal cell carcinoma patients have chronic kidney disease prior to nephrectomy and a significant number of patients with normal prenephrectomy renal function markers progress to chronic kidney disease over time. Evaluation of non-neoplastic parenchyma in tumor nephrectomy specimens can identify patients at risk for progression to chronic kidney disease, which is a critical step for early intervention and potential improvement of morbidity and mortality rates in this patient population.

References

Jan 1, 1991·American Journal of Nephrology·A ModestoP Veyssier
Jun 1, 1984·Kidney International·R M HakimB M Brenner
Dec 1, 1995·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·A OhishiT Saruta
Nov 5, 1997·Transplantation·I Fehrman-EkholmC G Groth
Feb 23, 1999·Diabetologia·P LindbladH O Adami
Mar 9, 1999·Epidemiology·J A ShapiroN S Weiss
Mar 20, 1999·American Journal of Epidemiology·J A ShapiroW E Barlow
Jun 12, 1999·Nephron·T MagyarlakiJ Nagy
Nov 4, 2000·The New England Journal of Medicine·W H ChowB Järvholm
Apr 7, 2004·Clinical and Experimental Nephrology·Yuko FujitaYasuo Katayama
Jul 13, 2004·Urology·Yoshinori ShirasakiHiromi Kumon
Sep 24, 2004·International Journal of Urology : Official Journal of the Japanese Urological Association·Yoshinori ShirasakiHiromi Kumon
Jan 6, 2005·Clinical Nephrology·S KapoulasE Giannoulis
Feb 6, 2007·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·Samih H NasrVivette D D'Agati
Dec 7, 2007·The American Journal of Surgical Pathology·Kammi J HenriksenAnthony Chang
Apr 17, 2009·American Journal of Clinical Pathology·UNKNOWN Association of Directors of Anatomic and Surgical Pathology
Sep 21, 2010·The Journal of Urology·Gagan GautamAnthony Chang
Jun 22, 2011·World Journal of Urology·Michael Garcia-RoigGaetano Ciancio
May 5, 2012·North American Journal of Medical Sciences·Subhash GoyalRekha Goyal
Apr 3, 2013·Archives of Pathology & Laboratory Medicine·Steven P SalvatoreSurya V Seshan

❮ Previous
Next ❯

Citations

Oct 7, 2017·Modern Pathology : an Official Journal of the United States and Canadian Academy of Pathology, Inc·Marie E PerroneKammi J Henriksen
Mar 5, 2020·Seminars in Nephrology·Kammi J Henriksen, Anthony Chang

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.