Non-oncogenic sequelae of cancer chemotherapy

Radiology
N Jaffe

Abstract

The delayed effects of anticancer drugs and late complications in 334 long-term survivors of childhood cancer were reviewed. Sequelae associated with chemotherapy were uncommon. Two men in the series exhibited disorders in reproductive function, possibly due to chlorambucil. A third male patient had cyclophosphamide-induced hematuria which persisted for two years after cessation of therapy. Other abnormalities were renal, hepatic, skeletal and cardiopulmonary, ascribed chiefly to radiotherapy, although the deleterious effect of drugs on irradiated organs cannot be excluded. The data indicate that the skillful and judicious application of chemotherapeutic agents produces a minimum of delayed consequences.

Citations

Jun 1, 1983·International Journal of Radiation Oncology, Biology, Physics·D G Gonzalez, K Breur
Oct 1, 1977·The Journal of Pediatrics·A M MauerC B Pratt
Apr 1, 1977·American Journal of Surgery·N JaffeH Weinstein
Jan 1, 1978·International Journal of Psychiatry in Medicine·B Pfefferbaum
Jul 15, 1986·Cancer·S B LanskyC Ritter-Sterr
Jul 8, 2011·The Cochrane Database of Systematic Reviews·Renée L MulderLeontien Cm Kremer
Apr 1, 2008·Journal of Advanced Nursing·Natalie Doyle
Apr 16, 2019·The Cochrane Database of Systematic Reviews·Renée L MulderElvira C van Dalen
Jul 1, 1979·The American Journal of Orthopsychiatry·Janis L GoganJohn E O'Malley
Jan 1, 1979·Acta Radiologica: Oncology, Radiation, Physics, Biology·H SchultzA Sell
Sep 28, 2000·Cancer Treatment Reviews·B L van LeeuwenH J Hoekstra

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Gan to kagaku ryoho. Cancer & chemotherapy
H Furue
Current Opinion in Oncology
Richard W M van der Maazen, John M M Raemaekers
© 2022 Meta ULC. All rights reserved