Non-Pharmacologic Multicomponent Interventions Preventing Delirium in Hospitalized People.

Journal of the American Geriatrics Society
Paul LudolphKlaus Lieb

Abstract

Delirium is a common neurobehavioral complication in hospitalized patients with a high prevalence in various clinical settings. Prevention of delirium is critical due to its common occurrence and associated poor outcomes. Our objective was to evaluate the efficacy of multicomponent interventions in preventing incident delirium in hospitalized patients at risk. Systematic review and meta-analysis. Hospital. We included a study if it was a randomized controlled trial and was evaluating effects of coordinated non-pharmacologic multicomponent interventions in the prevention of delirium. We performed a systematic literature search in PubMed and CENTRAL (PROSPERO: CRD42019138981; last update May 24, 2019). We assessed the quality of included studies by using the criteria established by the Cochrane Collaboration. We extracted the measured outcomes for delirium incidence, duration of delirium, length of hospital stay, falls during hospital stay, discharge to institutional care, and inpatient mortality. In total, we screened 1,027 eligible records and included eight studies with 2,105 patients in the review. We found evidence of an effect (ie, reduction) of multicomponent interventions on the incidence of delirium (risk ratio = .53; 95...Continue Reading

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Citations

Oct 28, 2020·Evidence-based Nursing·Sandeep Yerra, Pradeep Yarra
Nov 14, 2020·Nature Reviews. Disease Primers·Jo Ellen WilsonE Wesley Ely
May 25, 2021·Complementary Therapies in Medicine·Ahmad FazlollahSeyed Tayeb Moradian
May 18, 2021·Frontiers in Aging Neuroscience·Giuseppe BellelliPaolo Mazzola
Jun 16, 2021·Annals of Emergency Medicine·Lucas Oliveira J E SilvaFernanda Bellolio
Jun 27, 2021·Age and Ageing·Alexandra PetersonAlasdair MacLullich
Jul 20, 2021·The Cochrane Database of Systematic Reviews·Jennifer K BurtonTerry J Quinn
Nov 27, 2021·The Cochrane Database of Systematic Reviews·Jennifer K BurtonTerry J Quinn

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