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Non-redundant roles in sister chromatid cohesion of the DNA helicase DDX11 and the SMC3 acetyl transferases ESCO1 and ESCO2

PloS One

Jan 15, 2020

Atiq FaramarzJob de Lange

Abstract

In a process linked to DNA replication, duplicated chromosomes are entrapped in large, circular cohesin complexes and functional sister chromatid cohesion (SCC) is established by acetylation of the SMC3 cohesin subunit. Roberts Syndrome (RBS) and Warsaw Breakage Syndrome (WABS) are rare...read more

Mentioned in this Paper

DDX11 gene
ESCO1 gene
ESCO2 gene
ESCO2 protein, human
Cohesin protein complex
SDF4 gene
Laboratory mice
Mitosis
Gene Knockdown Techniques
Roberts-SC Phocomelia Syndrome
3
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Non-redundant roles in sister chromatid cohesion of the DNA helicase DDX11 and the SMC3 acetyl transferases ESCO1 and ESCO2

PloS One

Jan 15, 2020

Atiq FaramarzJob de Lange

PMID: 31935221

DOI: 10.1371/journal.pone.0220348

Abstract

In a process linked to DNA replication, duplicated chromosomes are entrapped in large, circular cohesin complexes and functional sister chromatid cohesion (SCC) is established by acetylation of the SMC3 cohesin subunit. Roberts Syndrome (RBS) and Warsaw Breakage Syndrome (WABS) are rare...read more

Mentioned in this Paper

DDX11 gene
ESCO1 gene
ESCO2 gene
ESCO2 protein, human
Cohesin protein complex
SDF4 gene
Laboratory mice
Mitosis
Gene Knockdown Techniques
Roberts-SC Phocomelia Syndrome
3

Related Papers

Paper Details
References
  • References67
  • Citations
  • References67
  • Citations
  • quote and clock

    No citations available

    This paper may not have been cited yet.
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