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Non-selective NSAIDs improve the amyloid-β-mediated suppression of memory and synaptic plasticity

Pharmacology, Biochemistry, and Behavior

Feb 24, 2015

Jafar Doost MohammadpourKambiz Rohampour

Abstract

Alzheimer's disease (AD) is characterized by the formation of amyloid beta (Aβ) plaques in the brain. Dysfunctional excitatory synaptic transmission and neuronal plasticity are generally accepted as primary events in the development of AD. There is evidence to suggest that both COX-1 ex...read more

Mentioned in this Paper

Spatial Memory
Neuro-Oncological Ventral Antigen 2
Study
In Vivo
Pathogenic Aspects
Biochemical Pathway
Cyclooxygenase 2
Laboratory Procedures
Exertion
Pathogenesis
5
29
Paper Details
References
  • References31
  • Citations5
1234

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Non-selective NSAIDs improve the amyloid-β-mediated suppression of memory and synaptic plasticity

Pharmacology, Biochemistry, and Behavior

Feb 24, 2015

Jafar Doost MohammadpourKambiz Rohampour

PMID: 25697476

DOI: 10.1016/j.pbb.2015.02.012

Abstract

Alzheimer's disease (AD) is characterized by the formation of amyloid beta (Aβ) plaques in the brain. Dysfunctional excitatory synaptic transmission and neuronal plasticity are generally accepted as primary events in the development of AD. There is evidence to suggest that both COX-1 ex...read more

Mentioned in this Paper

Spatial Memory
Neuro-Oncological Ventral Antigen 2
Study
In Vivo
Pathogenic Aspects
Biochemical Pathway
Cyclooxygenase 2
Laboratory Procedures
Exertion
Pathogenesis
5
29

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Limbic System

The limbic system is comprised of several different parts of the brain involved in emotion, motivation, learning, and memory. Discover the latest research on the limbic system here.

Organelles in Neurodegeneration

Neurodegeneration is the progressive loss of neural structures and functions, including neuronal death. This feed focuses on dynamics of neuronal organelles in neurodegenerative diseases.

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Paper Details
References
  • References31
  • Citations5
1234
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