Non-specific immunity to Plasmodium falciparum: in vitro studies

Transactions of the Royal Society of Tropical Medicine and Hygiene
G A Butcher, R L Clancy

Abstract

Peripheral blood mononuclear cells (PBM) were cultured with Plasmodium falciparum malaria for several cycles of parasite growth. Non-immune PBM inhibited P. falciparum more frequently than immune PBM. The inhibiting factor appears to be released during the first 24 hours of culture and is a non-dialysable factor, probably originating from monocytes. The relevance of these findings to in vivo immunity is discussed.

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Citations

Apr 1, 1990·International Journal for Parasitology·G A Butcher
Dec 1, 1989·Parasitology·F PeyronP Ambroise-Thomas
Mar 1, 1991·APMIS : Acta Pathologica, Microbiologica, Et Immunologica Scandinavica·M L DubeyR C Mahajan
Oct 1, 1993·APMIS : Acta Pathologica, Microbiologica, Et Immunologica Scandinavica·R S JayshreeR C Mahajan
Oct 4, 2006·The Journal of Immunology : Official Journal of the American Association of Immunologists·Michael WaltherEleanor M Riley

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