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Non-specificity of Pitstop 2 in clathrin-mediated endocytosis

bioRxiv

Feb 13, 2014

Anna K WilloxStephen J Royle

Abstract

Small molecule inhibitors of clathrin-mediated endocytosis are highly desired for the dissection of membrane trafficking pathways in the lab and for potential use as anti-infectives in the clinic. One inhibition strategy is to prevent clathrin from contacting adaptor proteins so that cl...read more

Mentioned in this Paper

CLTC gene
Site
Metabolic Inhibition
Laboratory
Biochemical Pathway
Compound (Substance)
Amino-Terminal Amino Acid
Anti-Infective Agents
Study
Clathrin-mediated Endocytosis
5
1
Paper Details
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Non-specificity of Pitstop 2 in clathrin-mediated endocytosis

bioRxiv

Feb 13, 2014

Anna K WilloxStephen J Royle

PMID: 990002675

DOI: 10.1101/002675

Abstract

Small molecule inhibitors of clathrin-mediated endocytosis are highly desired for the dissection of membrane trafficking pathways in the lab and for potential use as anti-infectives in the clinic. One inhibition strategy is to prevent clathrin from contacting adaptor proteins so that cl...read more

Mentioned in this Paper

CLTC gene
Site
Metabolic Inhibition
Laboratory
Biochemical Pathway
Compound (Substance)
Amino-Terminal Amino Acid
Anti-Infective Agents
Study
Clathrin-mediated Endocytosis
5
1
Paper Details
References
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  • Citations
  • finger pointing at paper

    References currently unavailable

    We're still populating references for this paper, please check back later.
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