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Non-specificity of Pitstop 2 in clathrin-mediated endocytosis

bioRxiv

Feb 13, 2014

Anna K WilloxStephen J Royle

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Abstract

Small molecule inhibitors of clathrin-mediated endocytosis are highly desired for the dissection of membrane trafficking pathways in the lab and for potential use as anti-infectives in the clinic. One inhibition strategy is to prevent clathrin from contacting adaptor proteins so that cl...read more

Mentioned in this Paper

Trafficking
Clathrin Heavy Chain 2
Small Molecule
Pitstop 2
Study
Endocytosis
Biochemical Pathway
Metabolic Inhibition
Compound (Substance)
Anti-Infective Agents
5
1
Paper Details
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  • Non-specificity of Pitstop 2 in clathrin-mediated endocytosis

    bioRxiv

    Feb 13, 2014

    Anna K WilloxStephen J Royle

    PMID: 990002675

    DOI: 10.1101/002675

    Abstract

    Small molecule inhibitors of clathrin-mediated endocytosis are highly desired for the dissection of membrane trafficking pathways in the lab and for potential use as anti-infectives in the clinic. One inhibition strategy is to prevent clathrin from contacting adaptor proteins so that cl...read more

    Mentioned in this Paper

    Trafficking
    Clathrin Heavy Chain 2
    Small Molecule
    Pitstop 2
    Study
    5
    1
    Paper Details
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