Non-surgical management of multicystic dysplastic kidney

BJU International
Angelo J CambioEric A Kurzrock

Abstract

To better define the outcome and association of multicystic dysplastic kidney (MCDK) with hypertension, vesico-ureteric reflux (VUR), infection and cancer, as there is no consensus on the management of patients born with MCDK. The risk of cancer has dictated the surgical management of the disease in the past. The Medline database was searched for articles published between 1965 and 2006 and written in the English language, and containing the keywords 'multicystic dysplastic kidney'. The inclusion criteria were met by 105 reports that were subsequently analysed. Of MCDK, 60% regress or involute within 3 years. About 25% of patients will have VUR into the contralateral kidney, of which 90% is grade <or=3. The risk of urinary tract infection appears to be associated with VUR or coexistent abnormalities rather than the MCDK. The risk of hypertension is no greater than that in the general population and nephrectomy is usually not curative. The overall risk of Wilms' tumour developing in a MCDK is <1 in 2000. All reported Wilms' tumours were identified before 4 years of age and 70% presented as a palpable mass. Published reports support the non-surgical management of MCDK. Common practice has been to remove palpable or growing MCDKs,...Continue Reading

References

Aug 1, 1978·The Journal of Urology·D A Bloom, S Brosman
Aug 1, 1989·The Journal of Urology·J E DimmickM Carter
Aug 1, 1989·The Journal of Urology·H N NoeO P Edwards
Nov 1, 1988·The Journal of Urology·A C GordonH C Irving
Aug 1, 1995·The Journal of Urology·J S ElderA A Selzman
Jan 1, 1994·Pediatric Radiology·M OddoneP Tomà
Jul 1, 1994·The Journal of Urology·J MandellB R Benacerraf
Dec 1, 1993·The Journal of Urology·J Wacksman, L Phipps
Apr 1, 1997·The British Journal of Radiology·G T RottenbergR De Bruyn
Oct 23, 1997·The Journal of Urology·A G de Oliveira-FilhoE R de Oliveira
Nov 20, 1997·The Journal of Urology·Y L HomsyP Russo
Aug 24, 1999·The Journal of Urology·E B YerkesJ W Brock
Mar 1, 1960·The Journal of Urology·A C USONM M MELICOW
Feb 7, 2004·BJU International·E Kuwertz-BroekingL Hertle
Jul 20, 2004·Pediatric Nephrology : Journal of the International Pediatric Nephrology Association·Eli Armando S RabeloEdson Samesina Tatsuo
Aug 3, 2004·Pediatrics·UNKNOWN National High Blood Pressure Education Program Working Group on High Blood Pressure in Children and Adolescents
Jan 25, 2005·Archives of Disease in Childhood·H Narchi
Mar 30, 2005·BJU International·Eli Armando S RabeloEdson Samesina Tatsuo
Apr 5, 2005·Ultrasound in Obstetrics & Gynecology : the Official Journal of the International Society of Ultrasound in Obstetrics and Gynecology·A BhideB Thilaganathan
May 6, 2005·Archives of Disease in Childhood·H Narchi

❮ Previous
Next ❯

Citations

Mar 27, 2010·Pediatric Surgery International·Girolamo MattioliVincenzo Jasonni
May 10, 2011·Pediatric Surgery International·Aurelie ChiappinelliAlessandro Settimi
Sep 29, 2011·Pediatric Surgery International·Neil FeatherstoneFeilim Liam Murphy
May 16, 2008·Pediatric Nephrology : Journal of the International Pediatric Nephrology Association·David S HainsAndrew L Schwaderer
Mar 14, 2012·Pediatric Nephrology : Journal of the International Pediatric Nephrology Association·Wesley N HayesUNKNOWN Trent & Anglia MCDK Study Group
Apr 22, 2009·Indian Journal of Pediatrics·Jitendra Kumar SinghK L Narasimhan
Sep 1, 2014·Surgical Pathology Clinics·Joseph P Gaut
Aug 27, 2014·Clinics in Perinatology·Priya Verghese, Yosuke Miyashita
Jan 2, 2013·Taiwanese Journal of Obstetrics & Gynecology·Pei-Yang HsuFong-Ming Chang
Mar 30, 2010·Journal of Pediatric Urology·D F M Thomas
Aug 10, 2015·Current Urology Reports·Diana Cardona-Grau, Barry A Kogan
Jun 2, 2018·Pediatrics International : Official Journal of the Japan Pediatric Society·Aslihan KaraZehra Pinar Koc
Jul 4, 2018·Archives of Disease in Childhood·Shiva ShankarSagarika Ray
Sep 29, 2020·Journal of Neonatal-perinatal Medicine·R RainaC Bergmann

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Canadian Urological Association Journal = Journal De L'Association Des Urologues Du Canada
Karen Psooy
Archives of Disease in Childhood
M AslamTrent & Anglia MCDK Study Group
© 2021 Meta ULC. All rights reserved