Abstract
To evaluate the feasibility and the incidence of complete heart block (CHB) after non-surgical septal myocardial reduction by coil embolization in hypertrophic obstructive cardiomyopathy (HOCM). Twenty patients with HOCM and drug-refractory symptoms underwent non-surgical myocardial septal reduction by coil embolization with detachable coils. Occlusion of septal perforator branches was successfully performed in all patients. We detected neither ventricular tachycardia nor CHB. One patient presented an interventricular septal defect after the procedure, and died 19 days later. Cardiac magnetic resonance imaging showed, in all patients, an increase in areas of hyperenhancement in the interventricular septum (IVS) compared with baseline. At 6-month follow-up, NYHA functional class and peak oxygen consumption were significantly improved compared with baseline (14.8 +/- 4.5 vs. 18.5 +/- 4.5 mL/kg/min; P = 0.001, respectively). Echocardiography showed a significant reduction of the IVS thickness and left ventricular outflow tract gradient (21 +/- 3 vs. 17 +/- 4 mm, P < 0.0001; 80 +/- 29 to 35 +/- 29 mmHg, P < 0.0001, respectively). The results of this pilot non-randomized study suggest that non-surgical septal myocardial reduction by...Continue Reading
Citations
May 1, 2011·Cardiovascular Intervention and Therapeutics·Nagamani Alur ChikkabasavaiahRamesh Basavappa
Jul 29, 2010·Cardiology in the Young·Sreekanth NarsupalliGruschen Veldtman
Oct 8, 2008·Nature Clinical Practice. Cardiovascular Medicine·Steve RamcharitarPatrick W Serruys
Mar 31, 2011·European Heart Journal·Michael A Fifer, Ulrich Sigwart
Mar 19, 2014·Current Cardiology Reports·Rami N Khouzam, Srihari S Naidu
Apr 4, 2013·Netherlands Heart Journal : Monthly Journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation·P A VriesendorpM Michels
Jul 29, 2011·International Journal of Cardiology·Jean-François DeuxAlain Rahmouni
Sep 28, 2010·Heart Failure Clinics·Steven D Colan
Jul 15, 2009·Cardiovascular Revascularization Medicine : Including Molecular Interventions·Neeraj Parakh, Balram Bhargava
May 5, 2011·Catheterization and Cardiovascular Interventions : Official Journal of the Society for Cardiac Angiography & Interventions·Rui GuoJing Huang
Sep 1, 2014·European Heart Journal·Perry M ElliottHugh Watkins
Feb 23, 2010·Journal of the American College of Cardiology·Shikhar AgarwalSamir R Kapadia
Oct 24, 2012·Heart Rhythm : the Official Journal of the Heart Rhythm Society·Venkatakrishna N TholakanahalliKalyanam Shivkumar
Jun 13, 2009·Archives of Cardiovascular Diseases·Albert A Hagège, Michel Desnos
Jun 2, 2016·BioMed Research International·Pawel Petkow Dimitrow, Renata Rajtar-Salwa
May 14, 2016·EuroIntervention : Journal of EuroPCR in Collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology·Thomas Cuisset, Thierry Lefèvre
May 23, 2016·JACC. Cardiovascular Interventions·Metin ÇağdaşTufan Çınar
Aug 12, 2016·Catheterization and Cardiovascular Interventions : Official Journal of the Society for Cardiac Angiography & Interventions·Israel GuerreroRichard W Smalling
Mar 25, 2016·JRSM Cardiovascular Disease·Sercan OkutucuAli Oto
Dec 23, 2015·Echo Research and Practice·Robert M CooperRodney H Stables
Sep 9, 2017·Heart·Robert M Cooper, Rodney H Stables
Dec 6, 2017·Catheterization and Cardiovascular Interventions : Official Journal of the Society for Cardiac Angiography & Interventions·Serkan AsilKudret Aytemir
Aug 12, 2018·Journal of Interventional Cardiac Electrophysiology : an International Journal of Arrhythmias and Pacing·Patrick Fitzgerald, Fred Kusumoto