Non-targeted glycosidic profiling of international wines using neutral loss-high resolution mass spectrometry

Journal of Chromatography. a
C BarnabaR Larcher

Abstract

Many metabolites naturally occur as glycosides, since sugar moieties can be crucial for their biological activity and increase their water solubility. In the plant kingdom they may occur as glycosides or sugar esters, depending on precursor chemical structure, and in wine they have traditionally attracted attention due to their organoleptic properties, such as astringency and bitterness, and because they affect the colour and aroma of wines. A new approach directed at detailed description of glycosides in a large selection of monovarietal wines (8 samples each of Pinot Blanc, Muller Thurgau, Riesling, Traminer, Merlot, Pinot Noir and Cabernet Sauvignon) was developed by combining high performance liquid chromatography with high resolution tandem mass spectrometry. Analytical separation was performed on an Accucore™ Polar Premium LC column, while mass analysis was performed in negative ion mode with an non-targeted screening approach, using a Full MS/AIF/NL dd-MS2 experiment at a resolving power of 140,000 FWHM. Over 280 glycoside-like compounds were detected, of which 133 (including low-molecular weight phenols, flavonoids and monoterpenols) were tentatively identified in the form of pentose (6), deoxyhexose (17), hexose (73), ...Continue Reading

Citations

Aug 5, 2019·Applied Microbiology and Biotechnology·Javier RuizSantiago Benito
Jun 3, 2021·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Alexandros TzachristasCharalampos Proestos
Jul 3, 2021·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Adriana Maite Fernández-FernándezMaría Dolores Del Castillo
Nov 14, 2021·Archives of Toxicology·Gabriele Sabbioni, Billy W Day

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