Non-thyroid cancer in Northern Ukraine in the post-Chernobyl period: Short report

Cancer Epidemiology
M HatchKiyohiko Mabuchi

Abstract

The Chernobyl nuclear power plant accident in Ukraine in 1986 led to widespread radioactive releases into the environment - primarily of radioiodines and cesium - heavily affecting the northern portions of the country, with settlement-averaged thyroid doses estimated to range from 10 mGy to more than 10 Gy. The increased risk of thyroid cancer among exposed children and adolescents is well established but the impact of radioactive contamination on the risk of other types of cancer is much less certain. To provide data on a public health issue of major importance, we have analyzed the incidence of non-thyroid cancers during the post-Chernobyl period in a well-defined cohort of 13,203 individuals who were <18 years of age at the time of the accident. The report is based on standardized incidence ratio (SIR) analysis of 43 non-thyroid cancers identified through linkage with the National Cancer Registry of Ukraine for the period 1998 through 2009. We compared the observed and expected number of cases in three cancer groupings: all solid cancers excluding thyroid, leukemia, and lymphoma. Our analyses found no evidence of a statistically significant elevation in cancer risks in this cohort exposed at radiosensitive ages, although the...Continue Reading

References

Jun 6, 1998·Radiation and Environmental Biophysics·E P IvanovA M Kellerer
Oct 8, 1998·Epidemiologic Reviews·G R Howe
May 7, 2002·International Journal of Cancer. Journal International Du Cancer·Andriy G NoshchenkoVira D Drozdova
Mar 25, 2004·Radiation Research·Valentin A StezhkoUNKNOWN Chornobyl Thyroid Diseases Study Group of the USA
Mar 1, 2006·International Journal of Cancer. Journal International Du Cancer·Eero PukkalaElisabeth Cardis
Apr 22, 2006·International Journal of Cancer. Journal International Du Cancer·Elisabeth CardisPeter Boyle
Feb 7, 2007·Radiation and Environmental Biophysics·A PrysyazhnyukM Tirmarche
Aug 19, 2009·International Journal of Cancer. Journal International Du Cancer·Andriy G NoshchenkoVira D Drozdova
Mar 15, 2011·Clinical Oncology : a Journal of the Royal College of Radiologists·E Cardis, M Hatch

❮ Previous
Next ❯

Citations

Jun 27, 2015·Paediatric and Perinatal Epidemiology·Lauren A WiseElizabeth E Hatch
Jul 28, 2016·Annals of Epidemiology·Amelia K WesselinkShruthi Mahalingaiah
Aug 3, 2016·Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz·N WeilandB Grosche
Aug 28, 2019·Journal of Global Oncology·Krystle M LeungNelya Melnitchouk
Jan 29, 2017·International Journal of Public Health·Danna A SluskyMichael R Quastel
Sep 21, 2017·European Journal of Epidemiology·Maureen Hatch, Elisabeth Cardis
Aug 4, 2019·Radiation and Environmental Biophysics·T F LiubaretsD A Bazyka
Dec 29, 2020·Problemy Radiat︠s︡iĭnoï Medyt︠s︡yny Ta Radiobiolohiï·A Ye PrysyazhnyukS A Danevych

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)
Anna ButA Auvinen
International Journal of Cancer. Journal International Du Cancer
D SaliZ Valerianova
Liver Transplantation : Official Publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society
Ying JiangYang Mao
© 2021 Meta ULC. All rights reserved