Non-tropical fibrocalculous pancreatic diabetes: case reports and review of recent literature

The Journal of International Medical Research
Fang XiaYongmei Hu

Abstract

Fibrocalculous pancreatic diabetes (FCPD), an uncommon form of secondary diabetes, is caused by chronic nonalcoholic calcific pancreatitis and primarily occurs in tropical countries. To present our first-hand experiences in the diagnosis and management of FCPD in two patients from a non-tropical location. Two male Chinese patients (29 and 32 years old) presented with poor insulin function, negative islet cell and glutamate decarboxylase antibodies, and no spontaneous ketosis or abdominal pain. A careful clinical assessment was made and the results were correlated with laboratory findings. Abdominal ultrasound and computed tomography scans further revealed pancreatic calcification, calculi, and pancreatic duct dilation. Differential diagnosis confirmed FCPD and excluded the potential misdiagnosis of type 2 diabetes mellitus. FCPD in these patients was managed with insulin and symptomatic treatment with close monitoring. At the time of submission of this report, the first patient was stable at his last follow-up, but the second had been re-hospitalized for worsening symptoms. Early differential diagnosis of FCPD based on clinical examination and biochemical and radiological investigations, in tandem with insulin therapy, can help...Continue Reading

References

Jul 28, 2012·Pancreas·Sinead N DugganKevin C Conlon
Oct 23, 2012·Indian Journal of Endocrinology and Metabolism·Amrit NanaiahNihal Thomas
Sep 5, 2013·JAMA : the Journal of the American Medical Association·Yu XuUNKNOWN 2010 China Noncommunicable Disease Surveillance Group
Feb 25, 2015·Journal of Diabetes·Riddhi DasguptaNihal Thomas
May 1, 2015·BMC Research Notes·Dissanayake Mudiyanselage Priyantha Udaya Kumara RalapanawaEkanayake Mudiyanselage Madhushanka Ekanayake
Sep 8, 2016·Diabetes, Metabolic Syndrome and Obesity : Targets and Therapy·Jana Makuc
Jul 14, 2017·Clinical Diabetes and Endocrinology·Ranjit UnnikrishnanViswanathan Mohan
Jun 14, 2019·Diabetes, Metabolic Syndrome and Obesity : Targets and Therapy·Yalamanchi AiswaryaGoel Amit
Jul 25, 2019·Diabetes & Metabolic Syndrome·Channabasappa ShivaprasadGoel Amit
Apr 12, 2020·Current Diabetes Reports·Ranjit Unnikrishnan, Viswanathan Mohan

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