Non-Tuberculous Mycobacteria in Respiratory Specimens of Patients with Obstructive Lung Diseases-Colonization or Disease?

Antibiotics
Monika SzturmowiczAnna Zabost

Abstract

Non-tuberculous mycobacteria (NTM) are increasingly a cause of human respiratory tract colonization and mycobacterial lung disease (NTM-LD), especially in patients with chronic lung diseases. The aim of the present study was to find the factors predictive of NTM-LD in patients with obstructive lung diseases and NTM respiratory isolates. A total of 839 isolates of NTM, obtained from 161 patients between 2010 and 2020 in a single pulmonary unit, have been retrospectively reviewed. Of these isolates, 73 concerned 36 patients with obstructive lung diseases (COPD-26, asthma-3, COPD/asthma overlap syndrome-7). NTM-LD was recognized according to the American Thoracic Society (ATS) and the Infectious Diseases Society of America (IDSA) criteria in 17 patients, colonization in 19. Lower BMI, elevated body temperature on admission, infiltrative/cavitary lesions on chest CT, and NTM species other than Mycobacterium gordonae were the significant predictors of NTM-LD recognition. Based on the above-mentioned predictive factors, an original scoring system was implemented. The diagnostic utility of the scoring system was higher than that of single parameters. We conclude that NTM-LD prediction in patients with obstructive lung diseases and pos...Continue Reading

References

Feb 6, 2007·American Journal of Respiratory and Critical Care Medicine·David E GriffithUNKNOWN Infectious Disease Society of America
Feb 14, 2012·The International Journal of Tuberculosis and Lung Disease : the Official Journal of the International Union Against Tuberculosis and Lung Disease·C-T HuangP-C Yang
May 19, 2016·Emerging Infectious Diseases·Felix C RingshausenJessica Rademacher
Mar 10, 2017·The European Respiratory Journal·Ji An HwangTae Sun Shim
Apr 28, 2017·The European Respiratory Journal·D Rebecca PrevotsGiovanni Battista Migliori
Sep 22, 2017·The European Respiratory Journal·Sarah K BrodeTheodore K Marras
Feb 25, 2018·Infection·Tatjana Adzic-VukicevicSalvatore Rubino
Jun 3, 2018·Respiratory Medicine·Zofia BakułaTomasz Jagielski
Sep 15, 2018·Annals of the American Thoracic Society·Vincent X LiuStephen J Ruoss
Oct 20, 2018·Annals of the American Thoracic Society·Kiyohiko IzumiSatoshi Mitarai
Jun 22, 2019·The European Respiratory Journal·Steven CowmanMichael R Loebinger

❮ Previous
Next ❯

Citations


❮ Previous
Next ❯

Related Concepts

Related Feeds

Allergy and Asthma

Allergy and asthma are inflammatory disorders that are triggered by the activation of an allergen-specific regulatory t cell. These t cells become activated when allergens are recognized by allergen-presenting cells. Here is the latest research on allergy and asthma.

Asthma

This feed focuses in Asthma in which your airways narrow and swell. This can make breathing difficult and trigger coughing, wheezing and shortness of breath.

© 2021 Meta ULC. All rights reserved