Nonadherence as 4-day Antiretroviral Therapy Interruptions: Do Depression and Race/Ethnicity Matter as Much in the Modern Antiretroviral Therapy Era?

AIDS and Behavior
John A SaucedaParya Saberi

Abstract

HIV + White, Latino, and African Americans (N = 1131) completed a survey advertised on social media to re-examine the effect of depressive symptoms (via the Patient Health Questionnaire; PHQ-9) and race/ethnicity on antiretroviral therapy nonadherence (defined as past 3-month, 4-day treatment interruption). An adjusted logistic regression showed a 15 % increase in odds for a treatment interruption per 1-unit increase on the PHQ-9. The effect of depressive symptoms on nonadherence was greater for Latinos (OR = 1.80, p < 0.05), but not for African Americans, compared to Whites. The benefits of modern ART (e.g., simpler, forgiving to minor lapses) may not circumvent the effect of depressive symptomatology.

References

Oct 26, 2000·The Journal of Nervous and Mental Disease·S C KalichmanM Cage
Sep 15, 2001·Journal of General Internal Medicine·K KroenkeJ B Williams
Dec 23, 2004·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Franco MaggioloFredy Suter
Aug 31, 2006·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·David R Bangsberg
Jan 15, 2009·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Jean-Jacques ParientiEdward M Gardner
Mar 10, 2010·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Jean-Jacques ParientiUNKNOWN ESPOIR and REACH study groups
Nov 30, 2010·Research in Social & Administrative Pharmacy : RSAP·Sheryl ComptonCharles R Phillips
Dec 1, 2010·Journal of Acquired Immune Deficiency Syndromes : JAIDS·Adam W CarricoMargaret A Chesney
Aug 6, 2011·Annals of Behavioral Medicine : a Publication of the Society of Behavioral Medicine·Glenn J WagnerUNKNOWN MACH14 Investigators
Aug 23, 2011·Journal of Acquired Immune Deficiency Syndromes : JAIDS·Jeffrey S GonzalezSteven A Safren
Oct 21, 2011·Journal of Immigrant and Minority Health·Bich N DangJennifer H Kim
May 19, 2012·Journal of Acquired Immune Deficiency Syndromes : JAIDS·Jane M SimoniHonghu Liu
Jul 7, 2012·AIDS·Jean-Jacques Parienti, David L Paterson

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Citations

May 15, 2019·Journal of Fungi·Bright K OcanseyDavid W Denning
Jan 7, 2020·Journal of Acquired Immune Deficiency Syndromes : JAIDS·Kaylee B CrockettBulent Turan
Feb 26, 2020·Journal of Acquired Immune Deficiency Syndromes : JAIDS·Kaylee B CrockettBulent Turan
Mar 21, 2017·The Journal of the Association of Nurses in AIDS Care : JANAC·Kasey ClabornSofia Carbone
Jun 8, 2017·Current Opinion in HIV and AIDS·Lindsey E Garrison, Jessica E Haberer

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