Nonalcoholic Fatty Liver Disease Is Associated With Higher 1-year All-Cause Rehospitalization Rates in Patients Admitted for Acute Heart Failure

Medicine
Filippo ValbusaG Targher

Abstract

Repeat hospitalization due to acute heart failure (HF) is a global public health problem that markedly impacts on health resource use. Identifying novel predictors of rehospitalization would help physicians to determine the optimal postdischarge plan for preventing HF rehospitalization. Nonalcoholic fatty liver disease (NAFLD) is an emerging risk factor for many heart diseases, including HF. We assessed whether NAFLD at hospital admission predicts 1-year all-cause rehospitalization in patients with acute HF. We enrolled all patients consecutively admitted for acute HF to our General Medicine Division, from January 2013 to April 2014, after excluding patients with acute myocardial infarction, severe heart valve diseases, malignancy, known liver diseases, and those with volume overload related to extracardiac causes. NAFLD was diagnosed by ultrasonography and exclusion of competing etiologies. The primary outcome of the study was the 1-year all-cause rehospitalization rate. Among the 107 patients enrolled in the study, the cumulative rehospitalization rate was 12.1% at 1 month, 25.2% at 3 months, 29.9% at 6 months, and 38.3% at 1 year. Patients with NAFLD had markedly higher 1-year rehospitalization rates than those without NAFLD...Continue Reading

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Citations

May 31, 2016·Metabolism: Clinical and Experimental·Niki KatsikiChristos S Mantzoros
Aug 12, 2016·Liver International : Official Journal of the International Association for the Study of the Liver·Setor K Kunutsor
May 2, 2018·Nature Reviews. Gastroenterology & Hepatology·Quentin M AnsteeGiovanni Targher
Jan 10, 2020·Journal of Clinical and Translational Hepatology·Daud H AkhtarAijaz Ahmed
Aug 21, 2021·Alimentary Pharmacology & Therapeutics·Stergios A PolyzosEmmanuel A Tsochatzis

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Methods Mentioned

BETA
coronary
percutaneous transluminal coronary angioplasty
biopsy

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