Noncirrhotic portal vein thrombosis causing sudden unexpected death. A rare cause of fatally ruptured esophageal varices

The American Journal of Forensic Medicine and Pathology
J S Denton, B O Parks

Abstract

Noncirrhotic portal vein thrombosis (PVT) is a rare disease that usually presents with small nonfatal "herald bleeding" with low mortality. Classic findings of noncirrhotic PVT include esophageal varices, splenomegaly, a normal liver, and an organized thrombus of the portal vein. We present a case of previously unreported sudden unexpected death from noncirrhotic PVT in an asymptomatic elderly woman, review the literature of this entity, and examine the pathophysiology of the formation of fatally ruptured varices. The portal vein must be carefully examined in all cases where there is no coexisting cirrhosis.

References

Jan 1, 1978·Gut·S Sherlock
Oct 1, 1976·The American Journal of Medicine·J P VilleneuveA Viallet
Sep 1, 1989·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·T A Knox, M M Kaplan
Apr 1, 1989·The American Journal of Medicine·E PertuisetJ C Rambaud
Oct 1, 1987·AJR. American Journal of Roentgenology·H MoriM Mutsukura

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Citations

Mar 29, 2006·Journal of Forensic Sciences·Roger W Byard
Dec 30, 2014·Journal of Pediatric Gastroenterology and Nutrition·Hanaa M El-KaraksyMortada El-Shabrawi

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