Nonclinality of molecular variation implicates selection in maintaining a morphological cline of Drosophila melanogaster.

Genetics
Julia GockelLinda Partridge

Abstract

One general approach for assessing whether phenotypic variation is due to selection is to test its correlation with presumably neutral molecular variation. Neutral variation is determined by population history, the most likely alternative explanation of spatial genetic structure, whereas phenotypic variation may be influenced by the spatial pattern of selection pressure. Several methods for comparing the spatial apportionment of molecular and morphological variation have been used. Here, we present an analysis of variance framework that compares the magnitudes of latitudinal effects for molecular and morphological variation along a body size cline in Australian Drosophila populations. Explicit incorporation of the relevant environmental gradient can result in a simple and powerful test of selection. For the Australian cline, our analysis provides strong internal evidence that the cline is due to selection.

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Citations

Dec 1, 2008·Annual Review of Ecology, Evolution, and Systematics·Ary A Hoffmann, Loren H Rieseberg
Sep 20, 2008·Journal of Evolutionary Biology·M DemontT W J Garner
Apr 16, 2003·Molecular Ecology·David D DuvernellWalter F Eanes
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Feb 19, 2010·Proceedings. Biological Sciences·Robert I ColauttiSpencer C H Barrett
Feb 13, 2010·Evolution; International Journal of Organic Evolution·Sylvain AntoniazzaAlexandre Roulin

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