Noncommunicable disease and multimorbidity in young adults with cerebral palsy

Clinical Epidemiology
Daniel G WhitneyMark D Peterson

Abstract

Individuals with cerebral palsy (CP) are at increased risk for frailty and chronic disease due to factors experienced throughout the lifespan, such as excessive sedentary behaviors and malnutrition. However, little is known about noncommunicable diseases (NCDs) and multimorbidity profiles in young adults with CP. The study objective was to compare NCD and multimorbidity profiles between young adults with and without CP. A clinic-based sample of adults (18-30 years) with (n=452) and without (n=448) CP was examined at the University of Michigan Medical Center. The prevalence and predictors of 13 NCDs were evaluated, including existing diagnoses or historical record of musculoskeletal, cardiometabolic, and pulmonary morbidities. The level of motor impairment was determined by the Gross Motor Function Classification System (GMFCS) and stratified by less vs more severe motor impairment (GMFCS I-III vs IV-V). Logistic regression was used to determine the odds of NCD morbidity and multimorbidity in adults with CP compared to adults without CP, and for GMFCS IV-V compared to GMFCS I-III in those with CP, after adjusting for age, sex, body mass index, and smoking. Adults with CP had a higher prevalence of osteopenia, osteoporosis, hyper...Continue Reading

Citations

Feb 8, 2019·Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research·Daniel G WhitneyMark D Peterson
Jul 18, 2019·Annals of Rehabilitation Medicine·You Gyoung YiMoon Suk Bang
Aug 30, 2019·Neurology·Jennifer M RyanElizabeth Allen
Nov 12, 2019·Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society·Daniel G WhitneyKarl J Jepsen
Apr 3, 2020·International Journal of Qualitative Studies on Health and Well-being·Beate Eltarvåg GjesdalSilje Mæland
Aug 29, 2020·Journal of Managed Care & Specialty Pharmacy·Daniel G WhitneyHeidi Haapala
Aug 1, 2019·Genetics in Medicine : Official Journal of the American College of Medical Genetics·Sarah L MaleckiAnne S Bassett
Apr 2, 2020·Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society·Daniel G Whitney
Jul 17, 2020·Frontiers in Pediatrics·Rachael MarpoleAndrew C Wilson
Feb 7, 2019·Developmental Medicine and Child Neurology·Jennifer M RyanElizabeth Allen
Sep 29, 2020·Developmental Neurorehabilitation·Fabio Vila-NovaRita Cordovil
Dec 8, 2019·Mayo Clinic Proceedings·Daniel G WhitneyMark D Peterson
Jul 10, 2020·Neurology. Clinical Practice·Daniel G WhitneyMark D Peterson
Dec 9, 2020·Developmental Medicine and Child Neurology·Daniel G Whitney, Neil S Kamdar
Nov 17, 2020·Bone Reports·Jonathan P EtterDaniel G Whitney
Oct 23, 2020·Bone Reports·Daniel G WhitneyKarl J Jepsen
May 9, 2021·Disability and Rehabilitation·Sanjana KannikeswaranDaniel G Whitney
Jun 8, 2021·Journal of Pediatric Rehabilitation Medicine·Elizabeth ChanDeborah Gaebler-Spira
Mar 18, 2021·American Journal of Preventive Medicine·Daniel G WhitneyMark D Peterson
Sep 9, 2021·Developmental Medicine and Child Neurology·Elham MahmoudiMark D Peterson
Sep 4, 2021·Endocrine Reviews·Peter R EbelingFrances Milat
Oct 22, 2021·Frontiers in Neurology·Daniel G WhitneyEdward A Hurvitz

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