Noncontact corneal pachymetry with slit lamp-adapted optical coherence tomography

American Journal of Ophthalmology
Christopher WirbelauerR Birngruber

Abstract

The purpose of this study was to determine the accuracy, the reproducibility, and the limits of agreement of noncontact central corneal thickness measurement with slit lamp-adapted optical coherence tomography (OCT). Nonrandomized comparative clinical trial. In a prospective comparative observational study, a total of 108 consecutive patients (108 eyes) with normal corneas (92 eyes) and different corneal alterations (16 eyes) participated. Six sequential measurements of the central corneal thickness with slit lamp-adapted OCT and with ultrasound (US) pachymetry at 1640 ms(-1) were performed. The main outcome measures were accuracy, reproducibility assessed with precision and coefficient of variation (CV), and limits of agreement of central corneal thickness measurement. The mean central corneal thickness values were 541 +/- 43 microm (OCT) and 549 +/- 44 microm (US) with a mean precision of +/- 5.8 microm (CV 1.08%) and of +/- 4.0 microm (CV 0.73%), respectively. The method comparison revealed equivalence (+/- 2SD) in the 5% range with a mean difference between both methods of 7.9 microm (1.45%). The relative error was 8.7 microm (1.6%), which corresponded to limits of agreement (+/- 2SD) ranging from -9.5 microm to 25.3 microm...Continue Reading

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Citations

Jan 29, 2003·Journal of Cataract and Refractive Surgery·Jose Manuel González-MéijomeManuel A Parafita
Jan 8, 2004·Journal of Cataract and Refractive Surgery·Christopher WirbelauerDuy Thoai Pham
Dec 25, 2004·Journal of Cataract and Refractive Surgery·Christopher Wirbelauer, Duy Thoai Pham
Jan 25, 2003·The British Journal of Ophthalmology·I JalbertM Coroneo
Jul 26, 2003·The British Journal of Ophthalmology·C WirbelauerD T Pham
May 3, 2005·Lasers in Medical Science·F D VerbraakT G van Leeuwen
Oct 3, 2008·Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft·A ViestenzW Behrens-Baumann
Sep 21, 2004·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·Christopher WirbelauerDuy Thoai Pham
Feb 10, 2009·American Journal of Orthodontics and Dentofacial Orthopedics : Official Publication of the American Association of Orthodontists, Its Constituent Societies, and the American Board of Orthodontics·Jae Ho BaekWoo Sung Son
Jul 29, 2008·Journal of Cataract and Refractive Surgery·Irmingard M NeuhannThomas F Neuhann
Nov 4, 2006·Journal of Cataract and Refractive Surgery·Maya MüllerHans Hoerauf
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Sep 3, 2004·Journal of Cataract and Refractive Surgery·Christopher Wirbelauer, Duy Thoai Pham
Apr 25, 2006·Journal of Cataract and Refractive Surgery·Gabor NemethLaszlo Módis
Mar 28, 2006·Journal of Cataract and Refractive Surgery·Sandrine HickIsabelle Brunette
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Dec 22, 2017·Clinical & Experimental Ophthalmology·Rachel FanVishal Jhanji
Mar 17, 2004·Current Opinion in Ophthalmology·James D Brandt
Jun 29, 2004·Cornea·Christopher Wirbelauer, Duy Thoai Pham
Dec 28, 2002·Cornea·Siegfried G PriglingerUlrich Welge-Luessen
Feb 9, 2011·Eye & Contact Lens·Javier González-PérezManuel Angel Parafita
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Nov 23, 2006·Current Eye Research·Maya MüllerHorst Laqua
Dec 12, 2012·European Journal of Ophthalmology·Gabor NemethLaszlo Modis

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