Jan 1, 1975

Nonenzymatic reactivation of des-acetyl citrate lyase by acetyl adenylate. First example of enzyme activation by chemotrophic modification

Physiological Chemistry and Physics
G CamiciG Ramponi

Abstract

The experimental conditions of nonenzymatic reactivation of des-acetyl citrate lyase from K. aerogenes were studied. It was found that at pH 8.5 0.2 MM acetyl AMP causes a fast reactivation of the enzyme. The pH dependence of activity and the Km for citrate are very similar for both native and reactivated enzyme.

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Mentioned in this Paper

Oxo-Acid-Lyases
Citrate Measurement
Phosphaden
Citrate
acetyl adenylate
Klebsiella
Citrate lyase
Hydrogen-Ion Concentration
Enzyme Activation
ATP Citrate (pro-S)-Lyase

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