Abstract
Nonfunctioning islet cell tumors (NFICTs) usually reach a large size prior to detection, at which stage patients have some symptoms or signs. Recently, NFICTs have been discovered in asymptomatic patients with increasing frequency owing to advances in diagnostic imaging techniques. This study investigated clinical, imaging and pathological features in recent cases of NFICT. The medical records, radiographs and pathological specimens of 16 patients with NFICT who were evaluated between April 1991 and March 1996 were reviewed. Tumor sizes ranged from 0.8 to 17 cm (average, 5.2 cm). Five patients (31%) had some symptoms or signs at the time of diagnosis; however, the other 11 (69%) had no symptoms. Of 10 patients with a tumor of size 5 cm or less, nine were asymptomatic and all tumors were histologically benign. In contrast, in six patients with a tumor larger than 5 cm, four had some symptoms and five tumors were malignant. The detection rates of pancreatic tumor mass on ultrasonography and computed tomography were 94% (15/16) each. All 14 patients in whom the tumor was completely resected survived without recurrence; however, the remaining two patients with liver metastases died following recurrence. US and CT are useful in dete...Continue Reading
References
Jul 1, 1976·Radiology·S BagheryM G Zelch
Apr 1, 1978·AJR. American Journal of Roentgenology·P C Freeny, T J Ball
Feb 20, 1992·The New England Journal of Medicine·C G MoertelD Klaassen
Jul 15, 1991·Cancer·H RothmanJ Fryer
Jan 1, 1990·Gastrointestinal Radiology·C FugazzolaG Serio
Nov 1, 1990·The New England Journal of Medicine·S W LambertsE P Krenning
Jan 1, 1989·Acta Oncologica·B ErikssonB Skogseid
Apr 1, 1985·The Surgical Clinics of North America·P F DialG L Jin
Sep 1, 1973·The American Journal of Roentgenology, Radium Therapy, and Nuclear Medicine·V DeutschM Mozes
Nov 1, 1984·AJR. American Journal of Roentgenology·E A EelkemaP F Sheedy
Feb 1, 1981·Annals of Surgery·R B KentL H Weiland
Jun 1, 1982·Journal of Ultrasound in Medicine : Official Journal of the American Institute of Ultrasound in Medicine·T H ShawkerD M McCarthy
Feb 1, 1984·Radiology·D D StarkC W Deveney
Citations
Feb 8, 2003·European Journal of Ultrasound : Official Journal of the European Federation of Societies for Ultrasound in Medicine and Biology·Lionello GandolfiAnnalisa Puccetti
Jul 9, 2002·Pathology International·Yoon-La ChoiGeunghwan Ahn
May 30, 2008·Endocrine-related Cancer·Thorvardur R HalfdanarsonGloria M Petersen
Mar 23, 2007·AJR. American Journal of Roentgenology·Manabu HashimotoYuzo Yamamoto
Aug 20, 2002·AJR. American Journal of Roentgenology·Sheila ShethElliot K Fishman
Jul 21, 2009·Abdominal Imaging·Salvatore MazzeoCarlo Bartolozzi
Mar 22, 2006·Radiographics : a Review Publication of the Radiological Society of North America, Inc·Karen M HortonElliot K Fishman
Jun 6, 2007·Hematology/oncology Clinics of North America·Eric P TammChaan S Ng
Jul 2, 2005·Gastrointestinal Endoscopy Clinics of North America·Sukru Mehmet ErturkMatthew A Barish
Jun 10, 2004·World Journal of Gastroenterology : WJG·Han LiangXi-Shan Hao
Sep 28, 2000·The American Journal of Gastroenterology·A Fritscher-RavensN Soehendra
Apr 28, 2010·Spine·Todd Alin EadsRichard B Rodgers
Apr 15, 2006·Acta Radiologica·E D RappeportU Knigge
Oct 12, 2018·Insights Into Imaging·Valentina CiaravinoMirko D'Onofrio