Noninvasive analysis of renal artery blood flow dynamics with MR cine phase-contrast flow measurements

The American Journal of Physiology
Stefan O SchoenbergH R Kirchheim

Abstract

It was the aim of this study to quantify the measurement of pulsatile flow in the renal artery with the noninvasive magnetic resonance cine phase-contrast (MRCPC) method and combine it with the simultaneous assessment of pulsatile flow with a transit-time ultrasound (TTUS) flowmeter. In seven foxhounds with a chronically implanted precalibrated TTUS flow probe, MRCPC flow measurements were made in the renal artery with a temporal resolution of 32 ms. Mean and pulsatile flow signal were compared by the simultaneous ipsi- or contralateral measurement of the renal blood flow signal by both methods (TTUS and MRCPC). In addition, comparative MRCPC and TTUS flow measurements were made with artificial renal artery stenosis and after the administration of angiotensin II. The mean flow data assessed by the noninvasive MRCPC flow measurements showed an excellent correlation with corresponding TTUS recording (r = 0.99). The MRCPC flow signal displayed a waveform of the renal artery flow profile that was very similar to the TTUS flow pulse. The hemodynamic changes induced by angiotensin II or due to renal artery stenosis were also reliably detected by MRCPC. MRCPC provides a reliable noninvasive method for the quantification of mean blood ...Continue Reading

Citations

Apr 18, 2002·American Journal of Physiology. Regulatory, Integrative and Comparative Physiology·N C F SandgaardP Bie
Apr 8, 2006·American Journal of Physiology. Renal Physiology·Pottumarthi V Prasad
Apr 24, 2007·AJR. American Journal of Roentgenology·Nils HacksteinWigbert S Rau

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