Noninvasive bedside assessment of acute asthma severity using single-breath counting

Pediatric Emergency Care
Lindsay R RoofeDonald H Arnold

Abstract

The single-breath counting (SBC) method for assessment of asthma exacerbation severity has been evaluated in adults during exacerbations and in pediatric patients during routine settings. Single-breath counting has not been evaluated in children during exacerbations. We sought to assess criterion validity and responsiveness of SBC with percent-predicted FEV1 (%FEV1) and the Pediatric Respiratory Assessment Measure (PRAM), a validated acute asthma severity score. We prospectively enrolled subjects aged 7 to 17 years with acute asthma exacerbations. Single-breath counting, %FEV1, and PRAM were obtained before treatment and 2 hours after initiating therapy. Multivariable linear regression models were used to examine associations of pretreatment SBC with %FEV1 and PRAM (criterion validity) and 2-hour change of these measures (responsiveness). With a 2-sided α of 0.05, SBC SD of 8.5, and 90% power to detect an adjusted R of greater than 0.36 for SBC with each outcome measure, a minimum sample of 20 participants was necessary. From June to November 2011, 51 participants were enrolled, with median (interquartile range) age of 8.46 years (6.92-11.4 years); male sex, n = 40 (78%); and African American race, n = 33 (64%). Before treatmen...Continue Reading

References

Jun 1, 1988·Journal of Speech and Hearing Research·R G LoudonB J Holcomb
Aug 1, 1994·Annals of Emergency Medicine·J M BartfieldK Dylong
May 1, 1993·The American Review of Respiratory Disease·L LeeR Stuebing
Dec 1, 1995·Pediatric Pulmonology·R B KleinA Mansell
Feb 1, 1997·Journal of Speech, Language, and Hearing Research : JSLHR·A L Winkworth, P J Davis
Feb 6, 1998·The American Journal of Emergency Medicine·B S UshkowN Raccio-Robak
Aug 2, 2005·The European Respiratory Journal·M R MillerUNKNOWN ATS/ERS Task Force
Sep 10, 2010·The American Journal of Emergency Medicine·Syed Sameer AliGavin Graff

❮ Previous
Next ❯

Citations


❮ Previous
Next ❯

Related Concepts

Related Feeds

Asthma

This feed focuses in Asthma in which your airways narrow and swell. This can make breathing difficult and trigger coughing, wheezing and shortness of breath.

Allergy and Asthma

Allergy and asthma are inflammatory disorders that are triggered by the activation of an allergen-specific regulatory t cell. These t cells become activated when allergens are recognized by allergen-presenting cells. Here is the latest research on allergy and asthma.