PMID: 8968179Dec 1, 1996Paper

Noninvasive estimate of work of breathing due to the endotracheal tube

Anesthesiology
L HeyerA Harf

Abstract

Although evidence suggests that secretions lining the inner wall of the endotracheal tube (ETT) often reduce its cross-sectional area, no data are available on the work of breathing as affected by the ETT. A noninvasive method is proposed for estimating the additional work of breathing necessitated by the ETT in patients whose lungs are mechanically ventilated. This method (the acoustic-Blasius method) involves (1) determining the inner geometry of the ETT using the acoustic reflection method and (2) using these geometric data to solve the Blasius equation that characterizes the ETT pressure drop-flow relation. To evaluate the acoustic-Blasius method in vivo, the authors computed the work of breathing due to the ETT in four healthy persons breathing through an ETT connected to a pressure-support device and in five tracheally intubated patients receiving mechanical assistance in the pressure-support mode. For the tracheally intubated patients, the reference value was the work calculated from the ETT pressure drop measured between the two ends of the ETT using a pressure catheter. In the healthy participants and the tracheally intubated patients, there was close agreement between inspiratory work per cycle values estimated by dir...Continue Reading

Associated Clinical Trials

Jan 10, 2013·Robert M. Kacmarek, Robert M. Kacmarek

References

Mar 1, 1979·Journal of Applied Physiology: Respiratory, Environmental and Exercise Physiology·P A ProulxD Laurent
Oct 1, 1976·Journal of Applied Physiology·M SullivanM Saklad
Oct 1, 1992·The American Review of Respiratory Disease·F LofasoD Isabey
Jul 1, 1989·The American Review of Respiratory Disease·P E WrightG R Bernard
Oct 1, 1983·Journal of Applied Physiology: Respiratory, Environmental and Exercise Physiology·P K BehrakisJ Milic-Emili
May 1, 1980·Journal of Applied Physiology: Respiratory, Environmental and Exercise Physiology·J J FredbergH L Dorkin
May 1, 1994·Journal of Applied Physiology·B LouisJ J Fredberg
Jan 1, 1994·American Journal of Respiratory and Critical Care Medicine·C Van SurellD Isabey
Aug 1, 1993·Journal of Biomechanical Engineering·B LouisJ Fredberg

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Citations

Jan 5, 2013·Current Opinion in Infectious Diseases·Riccardo PinciroliLorenzo Berra
Jan 28, 1998·American Journal of Respiratory and Critical Care Medicine·C StrausL Brochard
May 12, 2000·American Journal of Respiratory and Critical Care Medicine·P H JarreauG Moriette
Jul 24, 2004·American Journal of Respiratory and Critical Care Medicine·François LelloucheLaurent Brochard
Jan 13, 1999·European Journal of Anaesthesiology·L S Rasmussen
Feb 24, 2001·Acta Anaesthesiologica Scandinavica·L S RasmussenUNKNOWN ISPOCD group. The International Study of Postoperative Cognitive Dysfunction
Jan 13, 2000·Anaesthesia and Intensive Care·C J French

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