Noninvasive estimation of bone mass in ancient vertebrae

American Journal of Physical Anthropology
E Gonzalez-ReimersM Machado-Calvo

Abstract

Histomorphometry is useful in the assessment of trabecular bone mass (TBM), and thus, in the estimation of the prevalence and intensity of osteopenia in ancient population groups. However, it is a destructive method. It is therefore necessary to explore the accuracy of nondestructive approaches, such as radiography, bone mineral density (BMD) assessed by double-energy X-ray absorptiometry (DEXA), bone density (BD), or optical density (OD) in the diagnosis of osteopenia. We selected 51 vertebrae out of a total sample composed of 333 T12, L1, and L2 vertebrae belonging to adult pre-Hispanic inhabitants from El Hierro. These vertebrae underwent histomorphometrical analysis, a fine-grained film radiography with assessment of trabecular pattern following standard methods, OD, DEXA-assessed BMD, and BD. The presence of biconcave vertebrae and wedge-shaped vertebrae was also assessed by measuring anterior height (a), posterior height (p), and height at the middle point of the vertebral body (m), and further calculating the indices 2m/(a + p) ("spine score") and a/p. Significant correlations were observed between TBM and BMD (r=0.43), TBM and BD (r=0.49), TBM and OD (r=0.52), BMD and OD (r=0.51), and BMD and BD (r=0.36), but not betwee...Continue Reading

References

Nov 4, 1992·JAMA : the Journal of the American Medical Association·R R ReckerD B Kimmel
Aug 1, 1991·Acta Paediatrica Japonica; Overseas Edition·H TsukaharaM Sudo
Jun 1, 1991·Journal of the American College of Nutrition·Z K Roughead, M E Kunkel
Jan 1, 1991·Calcified Tissue International·E L Smith, C Gilligan
Jul 1, 1991·The American Journal of Clinical Nutrition·S B Eaton, D A Nelson
May 1, 1989·American Journal of Epidemiology·L J MeltonB L Riggs
Jul 1, 1968·The American Journal of Roentgenology, Radium Therapy, and Nuclear Medicine·L M Hurxthal
May 1, 1995·Current Opinion in Rheumatology·M Garabédian
Mar 1, 1995·Calcified Tissue International·M A SabinI Fogelman
Mar 13, 1993·Lancet·B LeesJ C Stevenson
Aug 1, 1995·Bone·C C Johnston, C W Slemenda
Dec 1, 1996·The Anatomical Record·S C Agarwal, M D Grynpas
Jan 1, 1997·Hormone Research·E F Eriksen, B L Langdahl
Apr 16, 1998·The British Journal of Radiology·G M BlakeI Fogelman
Apr 29, 1998·Arthritis and Rheumatism·S Levis, R Altman
Jun 18, 1998·The Journal of Nutrition·R P Heaney
Sep 11, 1998·Journal of Orthopaedic Science : Official Journal of the Japanese Orthopaedic Association·J IwamotoS Ichimura
Sep 29, 1999·American Journal of Physical Anthropology·J Velasco-VázquezF Santolaria-Fernández
Dec 1, 1999·Clinical Nutrition : Official Journal of the European Society of Parenteral and Enteral Nutrition·S PonzerT Cederholm
Aug 10, 2000·Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research·S BourrinR Rizzoli
Oct 19, 2000·Baillière's Best Practice & Research. Clinical Endocrinology & Metabolism·M F Sowers
Nov 30, 2000·Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·S A JacksonL Robertson
Aug 2, 2001·Acta Orthopaedica Scandinavica·R HasseriusO Johnell
Dec 12, 2001·Pediatrics International : Official Journal of the Japan Pediatric Society·T AnaiT Matsuo
May 16, 2002·American Journal of Physical Anthropology·E González-ReimersM Machado-Calvo
Jan 1, 1962·The British Journal of Nutrition·B S PLATT, R J STEWART
Jul 1, 1960·Clinical Radiology·E BARNETT, B E NORDIN

❮ Previous
Next ❯

Citations

May 24, 2011·American Journal of Human Biology : the Official Journal of the Human Biology Council·L Elizabeth DoyleSusan Pfeiffer
Feb 6, 2015·La Radiologia medica·Alda BorrèCarlo Faletti
Mar 10, 2015·Archives of Oral Biology·Ana Ivanišević MalčićSilvana Jukić
May 28, 2021·International Journal of Paleopathology·Anne-Marijn van SpeldeKerstin Lidén

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA
B MafartP Y Chouc
European Journal of Human Genetics : EJHG
Nicole Maca-MeyerJosé M Larruga
American Journal of Physical Anthropology
E Gonzalez-ReimersM Machado-Calvo
Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research
S BourrinR Rizzoli
© 2021 Meta ULC. All rights reserved