Noninvasive in vivo imaging reveals differences between tectorial membrane and basilar membrane traveling waves in the mouse cochlea

Proceedings of the National Academy of Sciences of the United States of America
Hee Yoon LeeJohn S Oghalai

Abstract

Sound is encoded within the auditory portion of the inner ear, the cochlea, after propagating down its length as a traveling wave. For over half a century, vibratory measurements to study cochlear traveling waves have been made using invasive approaches such as laser Doppler vibrometry. Although these studies have provided critical information regarding the nonlinear processes within the living cochlea that increase the amplitude of vibration and sharpen frequency tuning, the data have typically been limited to point measurements of basilar membrane vibration. In addition, opening the cochlea may alter its function and affect the findings. Here we describe volumetric optical coherence tomography vibrometry, a technique that overcomes these limitations by providing depth-resolved displacement measurements at 200 kHz inside a 3D volume of tissue with picometer sensitivity. We studied the mouse cochlea by imaging noninvasively through the surrounding bone to measure sound-induced vibrations of the sensory structures in vivo, and report, to our knowledge, the first measures of tectorial membrane vibration within the unopened cochlea. We found that the tectorial membrane sustains traveling wave propagation. Compared with basilar mem...Continue Reading

References

Jun 1, 1990·The Journal of the Acoustical Society of America·D D Greenwood
Feb 1, 1985·The Journal of the Acoustical Society of America·S E Shore, A L Nuttall
Apr 1, 1971·The Journal of the Acoustical Society of America·W S Rhode
Jan 1, 1983·Hearing Research·H Davis
Jul 9, 1982·Science·N Y KiangD K Ryugo
Aug 1, 1980·The Journal of the Acoustical Society of America·A L Nuttall, M J La Rouere
Dec 1, 1980·The Journal of the Acoustical Society of America·J B Allen
Feb 1, 1995·Hearing Research·N P Cooper, W S Rhode
Dec 1, 1995·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·H Gudbjartsson, S Patz
Jun 27, 1997·Science·G J TearneyJ G Fujimoto
Jun 28, 2001·Physiological Reviews·L Robles, M A Ruggero
Sep 21, 2004·Current Opinion in Otolaryngology & Head and Neck Surgery·John S Oghalai
Nov 30, 2004·Hearing Research·John S Oghalai
Jul 5, 2005·Nature Neuroscience·P Kevin LeganGuy P Richardson
Feb 1, 2006·Proceedings of the National Academy of Sciences of the United States of America·Anders FridbergerJacques Boutet de Monvel
Sep 2, 2006·Hearing Research·Niloy ChoudhuryAlfred L Nuttall
Nov 10, 2006·Journal of Biomedical Optics·Stanley S Hong, Dennis M Freeman
Mar 16, 2007·Optics Letters·Audrey K Ellerbee, Joseph A Izatt
Aug 19, 2007·Journal of the Association for Research in Otolaryngology : JARO·Anping XiaJohn S Oghalai
Oct 11, 2007·Proceedings of the National Academy of Sciences of the United States of America·Roozbeh GhaffariDennis M Freeman
Dec 15, 2007·Optics Letters·A M Rollins, J A Izatt
Jul 11, 2005·Optics Express·B VakocB Bouma
Jan 1, 2009·Journal of Mechanics of Materials and Structures·Charles R SteeleSunil Puria
Jun 15, 2010·Hearing Research·J AshmoreB Canlon
May 24, 2011·Nature Neuroscience·Fangyi ChenAlfred L Nuttall
Sep 4, 2012·Optics Letters·Ernest W ChangSeok H Yun
Sep 15, 2012·Hearing Research·Alfred L Nuttall, Anders Fridberger
Dec 12, 2012·Neuron·Jonathan A N FisherA J Hudspeth
Aug 21, 2013·Nature Photonics·Adeel AhmadStephen A Boppart
Jun 13, 2014·Journal of Neurophysiology·Simon S GaoJohn S Oghalai
Jul 6, 2014·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Sripriya RamamoorthyAnders Fridberger
Sep 23, 2014·Proceedings of the National Academy of Sciences of the United States of America·Marcel van der Heijden

❮ Previous
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Citations

Feb 19, 2016·Journal of the Royal Society, Interface·Guangjian NiJohannes Baumgart
Dec 20, 2015·Biophysical Journal·Sushrut S Kale, Elizabeth S Olson
Oct 7, 2015·Proceedings of the National Academy of Sciences of the United States of America·Jonathan B SellonDennis M Freeman
Jan 23, 2016·Scientific Reports·Yanli WangSunil Puria
Jul 3, 2015·International Forum of Allergy & Rhinology·Bryan T LemieuxBrian J F Wong
Sep 1, 2015·PloS One·Yanju LiuJong-Hoon Nam
Jul 14, 2016·Proceedings of the National Academy of Sciences of the United States of America·Rebecca L WarrenAnders Fridberger
Aug 16, 2016·Proceedings of the National Academy of Sciences of the United States of America·Tianying RenDavid Kemp
Oct 19, 2016·Biological cybernetics·Maurice FiloMariette Awad
Oct 21, 2016·Biophysical Journal·Wei Dong, Elizabeth S Olson
Oct 21, 2016·Biophysical Journal·Richard S Chadwick
Aug 22, 2016·Biophysical Journal·Shirin FarrahiDennis M Freeman
Apr 5, 2017·The Journal of the Acoustical Society of America·Guangjian NiStephen J Elliott
Apr 7, 2017·The Journal of Physiology·Alberto Recio-Spinoso, John S Oghalai
Feb 6, 2017·The Journal of the Acoustical Society of America·Nathan C LinElizabeth S Olson
Dec 4, 2015·Trends in Hearing·Chuan LuoClifford R Hume
May 16, 2018·Proceedings of the National Academy of Sciences of the United States of America·Hamid MotallebzadehSunil Puria
May 8, 2018·Proceedings of the National Academy of Sciences of the United States of America·Jinkyung KimJohn S Oghalai
Jul 27, 2018·Clinical and Experimental Otorhinolaryngology·Doekmin JeonJeehyun Kim
Jan 7, 2016·Nature Communications·Tianying RenPeter G Barr-Gillespie
Mar 16, 2019·Scientific Reports·Wenxiao Zhou, Jong-Hoon Nam
Mar 27, 2015·Journal of Neurophysiology·Yohan SongJohn S Oghalai
Jul 7, 2017·The Journal of the Acoustical Society of America·Thomas G LandryJeremy A Brown
Oct 24, 2018·Cold Spring Harbor Perspectives in Medicine·Jonathan B SellonDennis M Freeman
Sep 3, 2017·The Journal of the Acoustical Society of America·Stephen J ElliottLuyang Sun
Mar 16, 2016·Biomedical Optics Express·Jesung ParkNicusor Iftimia
Aug 5, 2018·Nature Communications·Nigel P CooperMarcel van der Heijden
Oct 9, 2019·The Journal of the Acoustical Society of America·Renata SistoArturo Moleti
Apr 23, 2020·Pflügers Archiv : European journal of physiology·Takeru OtaHiroshi Hibino
Sep 15, 2020·Biomedical Optics Express·Jorge A Palma-ChavezBrian E Applegate
Jun 27, 2015·Biomedical Optics Express·Jason M Tucker-SchwartzMelissa C Skala
Aug 18, 2018·Journal of Comparative Physiology. A, Neuroethology, Sensory, Neural, and Behavioral Physiology·Geoffrey A Manley
Oct 16, 2018·Frontiers in Neuroscience·Tamas Harczos, Frank Markus Klefenz
Dec 5, 2019·Biomedical Optics Express·Marilisa RomitoDemetri Psaltis
Sep 23, 2020·Journal of the Association for Research in Otolaryngology : JARO·Arturo Moleti, Renata Sisto
Jul 26, 2016·Biomedical Optics Express·Sangmin KimBrian E Applegate
Jul 7, 2017·The Journal of the Acoustical Society of America·Alessandro AltoèSarah Verhulst
Jun 3, 2017·Royal Society Open Science·Fabio A Sarria-SFernando Montealegre-Z

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