Noninvasive neurostimulation in chronic stroke: a double-blind randomized sham-controlled testing of clinical and corticomotor effects

Topics in Stroke Rehabilitation
Louis-David BeaulieuCyril Schneider

Abstract

Repetitive peripheral magnetic stimulation (RPMS) is a painless and noninvasive method to produce afferents via the depolarization of the peripheral nervous system. A few studies tested RPMS after-effects on cerebral plasticity and motor recovery in stroke individuals, but evidences remain limited. This study aimed to explore whether RPMS could mediate improvements in corticomotor and clinical outcomes associated with ankle impairments in chronic stroke. Eighteen subjects with chronic stroke were randomly allocated to RPMS or sham group and compared to 14 healthy subjects. Stimulation was applied over the paretic tibialis anterior (TA). Ankle impairments on the paretic side and ipsilesional TA cortical motor representation were tested clinically and by transcranial magnetic stimulation (TMS), respectively. In the RPMS group, ankle dorsiflexion mobility and maximal isometric strength increased and resistance to plantar flexor stretch decreased. The magnitude of change seemed to be related to cortical and corticospinal integrity. Sham stimulation yielded no effect. Changes in TMS outcome and their relationships with clinical improvements were limited. RPMS improved ankle impairments in chronic stroke likely by a dynamic influence...Continue Reading

References

Aug 1, 1992·Electroencephalography and Clinical Neurophysiology·J NilssonM Hallett
Jan 1, 1991·Journal of Clinical Neurophysiology : Official Publication of the American Electroencephalographic Society·B A Evans
Aug 1, 1991·Muscle & Nerve·Y Zhu, A Starr
Dec 24, 1990·Brain Research·M F Huerta, T P Pons
Oct 1, 1990·Muscle & Nerve·R K OlneyM J Aminoff
Nov 1, 1993·Electroencephalography and Clinical Neurophysiology·E KuneschR Benecke
Jan 1, 1994·The Journal of Orthopaedic and Sports Physical Therapy·P W Stratford, B E Balsor
Sep 1, 1996·British Journal of Sports Medicine·P J McNairS N Stanley
Apr 1, 1997·Experimental Brain Research·H DevanneC Capaday
Mar 21, 2000·Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism·C CarelF Chollet
Mar 23, 2000·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·J LiepertC Weiller
Jun 3, 2000·Stroke; a Journal of Cerebral Circulation·J LiepertC Weiller
Oct 6, 2000·Journal of Electromyography and Kinesiology : Official Journal of the International Society of Electrophysiological Kinesiology·H J HermensG Rau
Jan 23, 2003·Brain : a Journal of Neurology·Cathrin M BütefischVolker Hömberg
Dec 18, 2003·Supplements to Clinical Neurophysiology·Albrecht StrupplerPeter Havel
Feb 24, 2004·Brain Topography·Uwe HerwigCarlos Schönfeldt-Lecuona
Jan 25, 2005·Neuron·Ying-Zu HuangJohn C Rothwell
Feb 17, 2005·Muscle & Nerve·Jean-Michel Gracies
Feb 17, 2005·Muscle & Nerve·Jean-Michel Gracies
Feb 26, 2005·Clinical and Experimental Pharmacology & Physiology·Timothy S Miles
Sep 9, 2005·Neuroreport·Felipe FregniAlvaro Pascual-Leone
Oct 29, 2005·Stroke; a Journal of Cerebral Circulation·Naoyuki TakeuchiKatsunori Ikoma
Mar 31, 2006·Archives of Physical Medicine and Rehabilitation·Pei-Yi LinRay-Yau Wang
Apr 6, 2006·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·P TalelliJ C Rothwell
Dec 7, 2006·Brain : a Journal of Neurology·Cathy M StinearWinston D Byblow
Jan 26, 2007·Acta Physiologica·J B NielsenH Hultborn
Feb 15, 2007·Muscle & Nerve·Lynne R Sheffler, John Chae
Mar 14, 2007·Neurorehabilitation and Neural Repair·Påvel G LindbergJörgen Borg
Apr 7, 2007·Journal of Pediatric Orthopedics·Randall T LoderAndrew J Loder
May 25, 2007·Neurorehabilitation and Neural Repair·George F WittenbergTimothy P Pons

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Citations

Dec 1, 2019·The Cochrane Database of Systematic Reviews·Kotomi SakaiRyo Momosaki
Jun 24, 2017·The Cochrane Database of Systematic Reviews·Ryo MomosakiMasahiro Abo
Jun 17, 2020·Medicine·Shoji KinoshitaMasahiro Abo
Aug 11, 2020·International Journal of Rehabilitation Research. Internationale Zeitschrift Für Rehabilitationsforschung. Revue Internationale De Recherches De Réadaptation·Shoji KinoshitaMasahiro Abo
Mar 30, 2021·Archives of Rehabilitation Research and Clinical Translation·Christian SvaneJakob Lorentzen

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