Noninvasive quantification of rCBF using positron emission tomography

Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism
H WatabeT Nakamura

Abstract

This study proposes a new method for the pixel-by-pixel quantification of regional CBF (rCBF) with positron emission tomography and H(15)(2)O by using a reference tissue region. No arterial blood is required. Simulation studies revealed that the calculation of rCBF was fairly stable provided that the frame time was relatively short compared with total scan time. In practice, calculated CBF images correlated significantly with those obtained with the dynamic/integral method. Because the method accurately detects changes in CBF, it is particularly suitable for brain activation studies.

References

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Sep 1, 1990·Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism·A A LammertsmaT Jones
Aug 1, 1989·Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism·A A LammertsmaJ D Heather
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Citations

Feb 14, 2007·Annals of Nuclear Medicine·Hiroshi WatabeMiho Shidahara
Jan 29, 2003·European Journal of Nuclear Medicine and Molecular Imaging·Valerie TreyerAlfred Buck
Jul 8, 2008·The Review of Scientific Instruments·Kihak LeePaul A Jerabek
Aug 9, 2007·Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism·Yi-Gen Wu
Oct 8, 2016·Pharmacology Research & Perspectives·Hui LiuZhude Tu
Oct 24, 1998·Medical Informatics = Médecine Et Informatique·K MikolajczykC Burger
Feb 14, 2004·Stroke; a Journal of Cerebral Circulation·Asita S SarrafzadehAndreas W Unterberg
Sep 14, 2017·Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism·Thomas KoopmanRonald Boellaard
Mar 11, 2018·Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine·Tracy SsaliKeith St Lawrence

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Software Mentioned

SparcStation IPX

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