Nonlinear analysis of pupillary dynamics

Biomedizinische Technik. Biomedical Engineering
Francesco OnoratiRiccardo Barbieri

Abstract

Pupil size reflects autonomic response to different environmental and behavioral stimuli, and its dynamics have been linked to other autonomic correlates such as cardiac and respiratory rhythms. The aim of this study is to assess the nonlinear characteristics of pupil size of 25 normal subjects who participated in a psychophysiological experimental protocol with four experimental conditions, namely “baseline”, “anger”, “joy”, and “sadness”. Nonlinear measures, such as sample entropy, correlation dimension, and largest Lyapunov exponent, were computed on reconstructed signals of spontaneous fluctuations of pupil dilation. Nonparametric statistical tests were performed on surrogate data to verify that the nonlinear measures are an intrinsic characteristic of the signals. We then developed and applied a piecewise linear regression model to detrended fluctuation analysis (DFA). Two joinpoints and three scaling intervals were identified: slope α0, at slow time scales, represents a persistent nonstationary long-range correlation, whereas α1 and α2, at middle and fast time scales, respectively, represent long-range power-law correlations, similarly to DFA applied to heart rate variability signals. Of the computed complexity measures, ...Continue Reading

References

Oct 1, 1991·Journal of Clinical Monitoring·S M PincusR A Ehrenkranz
Jul 1, 1966·IEEE Transactions on Bio-medical Engineering·S F Stanten, L Stark
Mar 1, 1984·Journal of the Autonomic Nervous System·M C KossA Nomura
Jan 1, 1982·Biological cybernetics·S Usui, L Stark
May 22, 1995·Chemistry and Physics of Lipids·R H Jones, I Dey
Jul 4, 1998·Brain Research. Brain Research Reviews·A R Damasio
Jun 15, 1990·Physical Review. a·A LongtinM C Mackey
Feb 13, 2001·Journal of Affective Disorders·J F Thayer, R D Lane
Jul 28, 2001·Autonomic Neuroscience : Basic & Clinical·R K Rao, V K Yeragani
Aug 20, 2002·American Journal of Physiology. Regulatory, Integrative and Comparative Physiology·Douglas E LakeJ Randall Moorman
Aug 28, 2002·Diabetes Care·Daniel PittaschHendrik Lehnert
Oct 17, 2003·IEEE Transactions on Bio-medical Engineering·Thomas PenzelArmin Bunde
Mar 9, 2004·International Journal of Psychophysiology : Official Journal of the International Organization of Psychophysiology·Eric Granholm, Stuart R Steinhauer
Mar 9, 2004·International Journal of Psychophysiology : Official Journal of the International Organization of Psychophysiology·Stuart R SteinhauerMisha Pless
Mar 9, 2004·International Journal of Psychophysiology : Official Journal of the International Organization of Psychophysiology·P BitsiosC M Bradshaw
Aug 2, 2005·Autonomic Neuroscience : Basic & Clinical·Vesna Vuksanović, Vera Gal
Jan 28, 2006·International Journal of Psychophysiology : Official Journal of the International Organization of Psychophysiology·Pierre RainvilleAntonio R Damasio
Jul 14, 2006·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Virginie SterpenichPierre Maquet
Feb 6, 2008·Proceedings of the National Academy of Sciences of the United States of America·Wolfgang EinhäuserOlivia Carter
Feb 20, 2008·Psychophysiology·Margaret M BradleyPeter J Lang
Oct 15, 2008·Vision Research·Max WargaBarbara Wilhelm
Nov 4, 2008·Philosophical Transactions. Series A, Mathematical, Physical, and Engineering Sciences·Andreas VossPere Caminal
May 9, 2009·Annals of Behavioral Medicine : a Publication of the Society of Behavioral Medicine·Julian F ThayerBjorn Helge Johnsen
Sep 15, 1981·Applied Optics·C W Draper
Apr 8, 2010·Biological Psychology·Sylvia D Kreibig
Aug 16, 2011·Neuropsychologia·J DietzD Bowers
Mar 16, 2012·Scientific Reports·R M Bryce, K B Sprague
May 16, 2012·Proceedings of the National Academy of Sciences of the United States of America·Stefan M WierdaSander Martens
Nov 28, 2012·International Journal of Cardiology·Francesco Onorati, Giuseppe Faggian
Nov 5, 2013·BioMed Research International·L MesinR Cattaneo
Nov 14, 2013·Frontiers in Neuroengineering·Francesco OnoratiLuca Mainardi
Feb 11, 2014·Human Brain Mapping·Peter R MurphyJoshua H Balsters
May 23, 2014·Scientific Reports·Gaetano ValenzaRiccardo Barbieri

❮ Previous
Next ❯

Citations

Jan 30, 2016·Biomedizinische Technik. Biomedical Engineering·Jens Haueisen, Tilmann Sander-Thömmes
Mar 29, 2020·Frontiers in Neuroscience·Andy SchumannKarl Jürgen Bär
May 23, 2019·Frontiers in Neuroscience·Pietro PiuAlessandra Rufa
Mar 20, 2021·Physiological Measurement·Susmit BhowmikDinesh K Kumar

❮ Previous
Next ❯

Software Mentioned

mathop
SampEn

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Autonomic Neuroscience : Basic & Clinical
Rosangela Akemi HoshiMoacir Fernandes Godoy
Pflügers Archiv : European journal of physiology
Amir WeissmanShraga Blazer
Conference Proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society
Francesco OnoratiLuca Tommaso Mainardi
© 2021 Meta ULC. All rights reserved