Nonlinear characteristics of blood oxygen saturation from nocturnal oximetry for obstructive sleep apnoea detection

Physiological Measurement
Daniel AlvarezC Zamarrón

Abstract

Nocturnal oximetry is an attractive option for the diagnosis of obstructive sleep apnoea (OSA) syndrome because of its simplicity and low cost compared to polysomnography (PSG). The present study assesses nonlinear analysis of blood oxygen saturation (SaO(2)) from nocturnal oximetry as a diagnostic test to discriminate between OSA positive and OSA negative patients. A sample of 187 referred outpatients, clinically suspected of having OSA, was studied using nocturnal oximetry performed simultaneously with complete PSG. A positive OSA diagnosis was found for 111 cases, while the remaining 76 cases were classified as OSA negative. The following oximetric indices were obtained: cumulative time spent below a saturation of 90% (CT90), oxygen desaturation indices of 4% (ODI4), 3% (ODI3) and 2% (ODI2) and the delta index (Delta index). SaO(2) records were subsequently processed applying two nonlinear methods: central tendency measure (CTM) and Lempel-Ziv (LZ) complexity. Significant differences (p < 0.01) were found between OSA positive and OSA negative patients. Using CTM we obtained a sensitivity of 90.1% and a specificity of 82.9%, while with LZ the sensitivity was 86.5% and the specificity was 77.6%. CTM and LZ accuracies were high...Continue Reading

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Citations

Oct 31, 2007·Medical & Biological Engineering & Computing·J Víctor MarcosCarlos Zamarrón
Jun 25, 2010·Medical & Biological Engineering & Computing·J Víctor MarcosMateo Aboy
Nov 20, 2012·Medical & Biological Engineering & Computing·Daniel Sánchez Morillo, Nicole Gross
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Dec 14, 2011·Medical Engineering & Physics·Daniel ÁlvarezFélix Del Campo
Jan 23, 2010·Archivos de bronconeumología·Félix del Campo MatíaJ Víctor Marcos Martín
Jan 10, 2014·IEEE Journal of Biomedical and Health Informatics·Bijoy Laxmi Koley, Debangshu Dey
Sep 20, 2011·IEEE Transactions on Bio-medical Engineering·J Víctor MarcosFélix Del Campo
Jul 14, 2010·IEEE Transactions on Bio-medical Engineering·Daniel AlvarezFélix del Campo
Nov 6, 2009·IEEE Transactions on Information Technology in Biomedicine : a Publication of the IEEE Engineering in Medicine and Biology Society·Alfredo BurgosJesús Bermúdez
Feb 23, 2012·IEEE Transactions on Information Technology in Biomedicine : a Publication of the IEEE Engineering in Medicine and Biology Society·Baile Xie, Hlaing Minn
Aug 13, 2015·Sleep Disorders·Diego Alvarez-Estevez, Vicente Moret-Bonillo
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Jan 4, 2020·Journal of Interpersonal Violence·David KaterndahlRobert Wood
Sep 24, 2021·Sleep & Breathing = Schlaf & Atmung·Carlos Alberto NigroMaría Cecilia Zicari

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