PMID: 8647731Dec 1, 1995Paper

Nonlinear effects of noise on phase-locked cochlear-nerve responses to sinusoidal stimuli

Hearing Research
E R Lewis, K R Henry

Abstract

It is well known that, in a cochlear afferent axon with background spike activity, a sinusoidal stimulus (tone) of sufficiently low frequency will produce periodic modulation of the instantaneous spike rate, the alternating half cycles of which comprise excursions above and below the mean background spike rate. It also is known that if the amplitude of the stimulus is sufficiently small, the instantaneous spike rate follows very nearly a sinusoidal trajectory through these positive and negative excursions. For such cases, we define the AC responsiveness of a primary auditory afferent axon to be the amplitude of sinusoidal modulation of the instantaneous spike rate divided by the amplitude of the tone producing that modulation. In the experiments described in this paper, changes in AC responsiveness were followed during and after sudden changes in the background noise level. When the amplitude of the tone was sufficiently small relative to that of the noise, we found that the AC responsiveness can be strongly dependent on the time elapsed since the last change in noise level, while being nearly independent of the amplitude of the tone itself. Under those circumstances, after transitions between noise levels 20 dB apart, we obser...Continue Reading

References

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Citations

Feb 13, 2001·Bio Systems·E R LewisWalter M Yamada
Sep 3, 2002·Hearing Research·E R LewisWalter M Yamada
Nov 16, 2002·Hearing Research·E R LewisWalter M Yamada
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Jun 13, 2012·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·F PrévostH R Dajani
Dec 3, 2014·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·Melissa A PapeshLucas S Baltzell
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Jul 27, 1999·The Journal of the Acoustical Society of America·B H Bonham, E R Lewis
Jun 21, 2011·Nature Reviews. Neuroscience·Mark D McDonnell, Lawrence M Ward

Related Concepts

Acoustic Nerve
Acoustic Stimulation
Metazoa
Auditory Threshold
Axon
Cochlear Structure
Cochlear Nerve
Psammomys
Theoretical Study
Afferent Neuron

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