Nonlinear Mechanics of Athermal Branched Biopolymer Networks

The Journal of Physical Chemistry. B
R RensAbhinav Sharma

Abstract

Naturally occurring biopolymers such as collagen and actin form branched fibrous networks. The average connectivity in branched networks is generally below the isostatic threshold at which central force interactions marginally stabilize the network. In the submarginal regime, for connectivity below this threshold, such networks are unstable toward small deformations unless stabilized by additional interactions such as bending. Here we perform a numerical study on the elastic behavior of such networks. We show that the nonlinear mechanics of branched networks is qualitatively similar to that of filamentous networks with freely hinged cross-links. In agreement with a recent theoretical study,1 we find that branched networks also exhibit nonlinear mechanics consistent with athermal critical phenomena controlled by strain. We obtain the critical exponents capturing the nonlinear elastic behavior near the critical point by performing scaling analysis of the stiffening curves. We find that the exponents evolve with the connectivity in the network. We show that the nonlinear mechanics of disordered networks, independent of the detailed microstructure, can be characterized by a strain-driven second-order phase transition, and that the ...Continue Reading

References

Oct 1, 1991·Current Opinion in Cell Biology·C E Turner, K Burridge
Jul 1, 1996·Biophysical Journal·R L Satcher, C F Dewey
May 30, 1998·Proceedings of the National Academy of Sciences of the United States of America·R D MullinsT D Pollard
Jan 1, 1993·Physical Review. B, Condensed Matter·M Sahimi, S Arbabi
Dec 11, 1995·Physical Review Letters·F C MacKintoshP A Janmey
Jul 8, 1996·Physical Review Letters·K Kroy, E Frey
Sep 23, 2003·Journal of Biomechanics·Frederick H SilverGurinder P Seehra
Oct 4, 2003·Physical Review Letters·David A HeadF C MacKintosh
Oct 4, 2003·Physical Review Letters·Jan Wilhelm, Erwin Frey
Apr 20, 2004·Physical Review. E, Statistical, Nonlinear, and Soft Matter Physics·Pasquale CalabreseEttore Vicari
May 29, 2004·Science·M L GardelD A Weitz
Sep 25, 2004·Journal of Biomechanics·Yu-Long SunKai-Nan An
Sep 28, 2004·Journal of Applied Physiology·Francisco S A CavalcanteBéla Suki
May 13, 2005·Nature·Cornelis StormPaul A Janmey
Dec 31, 2005·Physical Review Letters·P R OnckE van der Giessen
Feb 21, 2006·Physical Review. E, Statistical, Nonlinear, and Soft Matter Physics·B A Didonna, T C Lubensky
Sep 12, 2006·Proceedings of the National Academy of Sciences of the United States of America·B WagnerA R Bausch
Dec 26, 2006·Nature Materials·Paul A JanmeyFred C MacKintosh
Mar 16, 2007·Physical Review Letters·R TharmannA R Bausch
Aug 7, 2007·Physical Review Letters·Moumita DasAlex J Levine
Oct 13, 2007·Physical Review. E, Statistical, Nonlinear, and Soft Matter Physics·Claus HeussingerErwin Frey
Nov 23, 2007·Biophysical Journal·Lanti YangJan Feijen
Jul 23, 2008·Physical Review. E, Statistical, Nonlinear, and Soft Matter Physics·H Hatami-Marbini, R C Picu
Mar 5, 2009·Physical Review Letters·Enrico Conti, Fred C Mackintosh
Oct 2, 2009·Physical Review Letters·N P Butch, M B Maple
Dec 8, 2009·Science·Thomas D Pollard, John A Cooper
Jan 30, 2010·Nature·Daniel A Fletcher, R Dyche Mullins
Feb 2, 2010·Food and Chemical Toxicology : an International Journal Published for the British Industrial Biological Research Association·UNKNOWN Expert Group Members
Apr 7, 2010·Physical Review Letters·Yi-Chia LinDavid A Weitz
Jan 15, 2011·Physical Review. E, Statistical, Nonlinear, and Soft Matter Physics·Stefan B LindströmDavid A Weitz
Jun 16, 2011·Biomacromolecules·Izabela K PiechockaGijsje H Koenderink
Mar 10, 2012·Physical Review Letters·C P BroederszF C Mackintosh
Oct 26, 2012·Biopolymers·Stéphanie Motte, Laura J Kaufman
Feb 2, 2013·Physical Review Letters·M SheinmanF C MacKintosh
May 18, 2013·Physical Review. E, Statistical, Nonlinear, and Soft Matter Physics·Xiaoming MaoT C Lubensky
May 18, 2013·Physical Review. E, Statistical, Nonlinear, and Soft Matter Physics·Xiaoming MaoT C Lubensky
Sep 17, 2013·Physical Review Letters·M DennisonF C MacKintosh
Dec 18, 2013·Physical Review. E, Statistical, Nonlinear, and Soft Matter Physics·A SharmaF C MacKintosh
Nov 20, 2014·Soft Matter·Knut M HeidemannMax Wardetzky
May 15, 2015·Physical Review. E, Statistical, Nonlinear, and Soft Matter Physics·Jingchen FengLeonard M Sander
Jul 22, 2015·Proceedings of the National Academy of Sciences of the United States of America·Albert James LicupFred C MacKintosh
Oct 4, 2015·Nature·Philip Ball
Feb 13, 2016·Physical Review. E·A J LicupF C MacKintosh

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Citations

May 14, 2016·Soft Matter·Mahsa VahabiFred C MacKintosh
Jul 18, 2017·Langmuir : the ACS Journal of Surfaces and Colloids·Seyed Meysam Hashemnejad, Santanu Kundu
Sep 6, 2019·The European Physical Journal. E, Soft Matter·Robbie Rens, Edan Lerner
Jul 9, 2020·Soft Matter·Sadjad ArzashFred C MacKintosh
May 22, 2019·Physical Review. E·Sadjad ArzashFred C MacKintosh
Nov 22, 2019·Physiological Reviews·Paul A JanmeyCynthia A Reinhart-King
May 31, 2019·Physical Review Letters·Jordan L ShiversFred C MacKintosh
Mar 22, 2019·Proceedings of the National Academy of Sciences of the United States of America·Matthias MerkelM Lisa Manning
Nov 15, 2016·Physical Review. E·A SharmaF C MacKintosh
Jan 27, 2019·Soft Matter·Jordan L ShiversF C MacKintosh
Jan 8, 2021·Biophysical Journal·Hamed Hatami-Marbini, Milad Rohanifar
Jan 30, 2020·Biophysical Journal·Shahar GorenAyelet Lesman
Jun 7, 2018·Biophysical Journal·Karin A JansenGijsje H Koenderink
Aug 31, 2021·Current Opinion in Cell Biology·Elizabeth Lawson-Keister, M Lisa Manning

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