Nonlinear modelling approach to human promoter sequences

Journal of Theoretical Biology
Huijie YangBinghong Wang

Abstract

By means of the nonlinear modelling technique, we find the nonlinear deterministic structures in the totally 4737 human promoter sequences. These deterministic structures prefer to occur much more outside of a special region around the transcriptional start site. The number and positions of the deterministic structures are basically different for different promoter sequences. Generally, they do not coincide with the CpG islands, the simple repetitive sequences and the low-complexity sequences, which tell us that they should be special structures with biological functions rather than these special segments.

References

Mar 12, 1992·Nature·C K PengH E Stanley
Oct 15, 1991·Physical Review. a·M Salerno
Jan 29, 1999·Mammalian Genome : Official Journal of the International Mammalian Genome Society·T Werner
May 1, 1995·Physical Review. E, Statistical Physics, Plasmas, Fluids, and Related Interdisciplinary Topics·S V BuldyrevH E Stanley
Aug 24, 1987·Physical Review Letters·J D Farmer, J J Sidorowich
Feb 26, 1996·Physical Review Letters·P GarcíaF Moleiro
Jul 15, 1999·Computers & Chemistry·A G PedersenS Brunak
Oct 25, 2000·Physical Review. E, Statistical Physics, Plasmas, Fluids, and Related Interdisciplinary Topics·J Barral PA Marcano
Feb 15, 2001·Trends in Genetics : TIG·U Ohler, H Niemann
Dec 26, 2001·Nucleic Acids Research·Yutaka SuzukiSumio Sugano
Aug 15, 2002·Bioinformatics·Boris Lenhard, Wyeth W Wasserman
Nov 2, 2002·Molecular Biology and Evolution·Josette-Renée LandryDixie L Mager
Dec 6, 2002·Nature·UNKNOWN Mouse Genome Sequencing ConsortiumEric S Lander
Dec 13, 2002·Proceedings of the National Academy of Sciences of the United States of America·Robert L StrausbergUNKNOWN Mammalian Gene Collection Program Team
Jan 10, 2003·Nucleic Acids Research·V MatysE Wingender
Jan 28, 2003·Trends in Genetics : TIG·I King JordanEugene V Koonin
Feb 5, 2003·Genome Research·Nathan D TrinkleinRichard M Myers
Jun 14, 2003·Journal of Virology·Josette-Renée Landry, Dixie L Mager
Jun 24, 2003·Genome Research·Piero CarninciYoshihide Hayashizaki
Oct 31, 2003·Trends in Genetics : TIG·Josette-Renée LandryBrian T Wilhelm
Feb 3, 2004·Physical Review. E, Statistical, Nonlinear, and Soft Matter Physics·Yi XiaoSaifeng Xiao
Feb 14, 2004·Nucleic Acids Research·Leonardo Mariño-RamírezDavid Landsman

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Citations

May 8, 2007·Journal of Theoretical Biology·Fangcui ZhaoBinghong Wang

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