Nonlinear viscoelastic characterization of human vocal fold tissues under large-amplitude oscillatory shear (LAOS)

Journal of Rheology
Roger W Chan

Abstract

Viscoelastic shear properties of human vocal fold tissues were previously quantified by the shear moduli (G' and G″). Yet these small-strain linear measures were unable to describe any nonlinear tissue behavior. This study attempted to characterize the nonlinear viscoelastic response of the vocal fold lamina propria under large-amplitude oscillatory shear (LAOS) with a stress decomposition approach. Human vocal fold cover and vocal ligament specimens from eight subjects were subjected to LAOS rheometric testing with a simple-shear rheometer. The empirical total stress response was decomposed into elastic and viscous stress components, based on odd-integer harmonic decomposition approach with Fourier transform. Nonlinear viscoelastic measures derived from the decomposition were plotted in Pipkin space and as rheological fingerprints to observe the onset of nonlinearity and the type of nonlinear behavior. Results showed that both the vocal fold cover and the vocal ligament experienced intercycle strain softening, intracycle strain stiffening, as well as shear thinning both intercycle and intracycle. The vocal ligament appeared to demonstrate an earlier onset of nonlinearity at phonatory frequencies, and higher sensitivity to chan...Continue Reading

References

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Citations

Nov 27, 2019·Journal of Speech, Language, and Hearing Research : JSLHR·Roger W Chan
Apr 15, 2020·NPJ Biofilms and Microbiomes·Saikat JanaJinju Chen
Nov 10, 2020·Journal of Colloid and Interface Science·Sohail YasinYihu Song
Jan 29, 2021·Biochemical and Biophysical Research Communications·Nehal DwivediAbhijit Majumder
Feb 21, 2021·Colloids and Surfaces. B, Biointerfaces·Barbara V Farias, Saad A Khan
Aug 23, 2020·Journal of Biomechanics·Thibaud CochereauMaxime Terrien

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