PMID: 7370912Apr 1, 1980Paper

Nonoperative management of femoral, humeral, and acetabular metastases in patients with breast carcinoma

Cancer
D S ChengH J Eyre

Abstract

A retrospective analysis of 59 cases of metastatic breast carcinoma involving the long bones and acetabula was done in an attempt to determine the role of radiation therapy in the management of bone metastases. A total of 97 bone lesions were treated with radiation as the initial therapeutic modality. Seven patients had pathologic fractures when first seen, and 2 had sustained fractures while receiving radiation therapy, and 2, following completion of radiation therapy. All patients had pain relief and improvement in their performance status. A third of patients had radiographic evidence of bone healing. None of the high-risk lesions that may ordinarily be subjected to prophylactic orthopedic stabilization in many medical centers sustained a pathologic fracture after the completion of radiation therapy. We conclude that the use of radiation therapy in initial management of bone metastases in patients with breast cancer is usually effective, and that prophylactic surgical intervention is not warranted in most cases.

References

Mar 1, 1972·Cancer·C A PerezH C Morgan
Nov 1, 1958·The Journal of Bone and Joint Surgery. British Volume·R A BREMNER, A M JELLIFFE

❮ Previous
Next ❯

Citations

Jan 1, 1995·International Journal of Radiation Oncology, Biology, Physics·P W TownsendR E Hassanein
Nov 5, 2003·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·Yvette M van der LindenUNKNOWN Dutch Bone Metastasis Study Group
Dec 1, 1996·International Journal of Radiation Oncology, Biology, Physics·M NiewaldM Fuchs
Apr 30, 2005·Journal of Palliative Medicine·P Kirkbride, R Barton
Jan 1, 1996·Acta Oncologica·T Möller
Jul 15, 2015·Clinical Orthopaedics and Related Research·Timothy A DamronBrian D Snyder
Jan 1, 1992·International Journal of Radiation Oncology, Biology, Physics·T Bates
Dec 16, 2006·Clinical Oncology : a Journal of the Royal College of Radiologists·J P AgarawalP J Hoskin
Mar 11, 2008·Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society·Tadashi S KanekoJoyce H Keyak
Jun 6, 2007·Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society·Douglas D RobertsonWilliam J Maloney
Aug 4, 2009·The Breast Journal·Federico L AmpilVictor A Ursua
Nov 5, 2013·The Journal of the American Academy of Orthopaedic Surgeons·Paul S IssackJoseph M Lane
Mar 1, 1989·Cancer Treatment Reviews·H S PoulsenM Rørth
Nov 7, 2006·Journal of Pain and Symptom Management·Priya C SinghVictor T Chang
Oct 24, 2000·The Orthopedic Clinics of North America·C J Bashore, H T Temple
Apr 27, 2016·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·Karlijn H J GroenenEsther Tanck
Aug 24, 2001·Cancer·R W Bunting, B Shea
Oct 27, 2016·Orthopedics·Ryan A DurfeeDavid Cheong
Jun 5, 2007·Clinical Orthopaedics and Related Research·Joyce H KeyakBang H Hoang
Mar 29, 2019·JBJS Reviews·Adam S LevinChristian F Meyer
May 30, 2003·The Oncologist·S Eva SingletaryGabriel N Hortobágyi
May 25, 2002·The American Journal of Hospice & Palliative Care·Perry G Fine
Aug 2, 2005·Clinical Orthopaedics and Related Research·Joyce H KeyakHarry B Skinner
Jun 1, 1997·The Journal of Bone and Joint Surgery. American Volume·A D Aaron
Oct 6, 2005·Clinical Orthopaedics and Related Research·Joyce H KeyakHarry B Skinner
Mar 1, 2015·Clinical Cancer Research : an Official Journal of the American Association for Cancer Research·Ara NazarianBrian D Snyder
Mar 24, 2021·The Journal of Bone and Joint Surgery. American Volume·Ron N AlkalayDavid B Hackney

❮ Previous
Next ❯

Related Concepts

Related Feeds

Breast Invasive Carcinoma

Invasive breast cancers indicate a spread into breast tissues and lymph nodes. Here are the latest discoveries pertaining to breast invasive carcinomas.

Breast Invasive Carcinoma (Keystone)

Invasive breast cancers indicate a spread into breast tissues and lymph nodes. Here are the latest discoveries pertaining to breast invasive carcinomas.