PMID: 11920480Mar 29, 2002Paper

Nonperioperative strokes in children with central nervous system tumors

Cancer
Daniel C BowersDeborah L Doxey

Abstract

Nonperioperative strokes are rare yet potentially devastating events for children with central nervous system (CNS) tumors. The incidence of and risk factors for nonperioperative strokes in children with CNS tumors is unknown. The authors performed a retrospective review of children from their institution with CNS tumors. The incidence of stroke in the nonperioperative period and the influence of patient demographic factors, coexisting genetic diseases, tumor type, and treatment modality on the subsequent occurrence of a stroke were determined. Eight hundred seven consecutive patients from the authors' institution with CNS tumors were observed for a combined 3224 nonperioperative years. Thirteen patients (1.6%) had a nonperioperative stroke, for an incidence of 4.03 strokes/1000 years of nonperioperative patient follow-up. Eight patients were males, and the median age at diagnosis of a CNS tumor was 4.8 years (range, 0.3-18.6 years). The median duration from diagnosis of a CNS tumor until the occurrence of stroke was 2.3 years (range, 0.3-15.8 years). Among numerous potential risk factors individually examined by chi-square analysis, only treatment with radiation therapy was associated with the subsequent development of a strok...Continue Reading

Citations

Apr 12, 2006·Child's Nervous System : ChNS : Official Journal of the International Society for Pediatric Neurosurgery·Daniel L KeeneEnrique Ventureyra
Mar 19, 2011·Child's Nervous System : ChNS : Official Journal of the International Society for Pediatric Neurosurgery·U TackeR Korinthenberg
Feb 12, 2008·Journal of Thrombosis and Thrombolysis·Giuseppe LippiGian Cesare Guidi
Jul 5, 2007·Journal of Pediatric Hematology/oncology·Kathleen A MeeskeStuart Siegel
Mar 18, 2009·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Melissa M HudsonLeslie L Robison
Sep 19, 2008·Neuro-Chirurgie·J GrillC Kalifa
Jan 25, 2011·Journal of Internal Medicine·M HalleP Tornvall
Aug 15, 2013·Pediatric Neurology·Corina NojeLori C Jordan

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