Nonproliferative and Proliferative Lesions of the Rat and Mouse Endocrine System

Journal of Toxicologic Pathology
Annamaria Brändli-BaioccoThomas J Rosol

Abstract

The INHAND (International Harmonization of Nomenclature and Diagnostic Criteria for Lesions in Rats and Mice) Project (www.toxpath.org/inhand.asp) is a joint initiative among the Societies of Toxicological Pathology from Europe (ESTP), Great Britain (BSTP), Japan (JSTP) and North America (STP) to develop an internationally accepted nomenclature for proliferative and nonproliferative lesions in laboratory animals. The purpose of this publication is to provide a standardized nomenclature for classifying microscopic lesions observed in the endocrine organs (pituitary gland, pineal gland, thyroid gland, parathyroid glands, adrenal glands and pancreatic islets) of laboratory rats and mice, with color photomicrographs illustrating examples of the lesions. The standardized nomenclature presented in this document is also available electronically on the internet (http://www.goreni.org/). Sources of material included histopathology databases from government, academia, and industrial laboratories throughout the world. Content includes spontaneous and aging lesions as well as lesions induced by exposure to test materials. A widely accepted and utilized international harmonization of nomenclature for endocrine lesions in laboratory animals ...Continue Reading

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Citations

Oct 2, 2020·Biological Trace Element Research·Jelena SaviciFlorin Muselin
Jul 25, 2019·Toxicologic Pathology·Akihisa KangawaMasatoshi Shibata
Aug 9, 2020·Journal of Toxicologic Pathology·Laura PolledoKlaus Weber
Oct 28, 2019·Toxicologic Pathology·Susan A ElmoreJeffrey C Wolf
Mar 20, 2020·International Journal of Molecular Sciences·Branka Šošić-JurjevićVerica Milošević
May 17, 2019·Journal of Toxicologic Pathology·Yuki KatoMikinori Torii
Jun 14, 2019·Human Molecular Genetics·Marjorie J LindhurstLeslie G Biesecker
Sep 14, 2020·Clinical and Experimental Pharmacology & Physiology·Kazuma KobayashiTakeshi Ohta
Mar 7, 2021·Animals : an Open Access Journal From MDPI·ZeWen YuBao Yuan
Apr 27, 2021·Food and Chemical Toxicology : an International Journal Published for the British Industrial Biological Research Association·Zhangqiong HuangQihan Li
Aug 5, 2021·Current Research in Toxicology·Vivian LuSean V Taylor
Oct 13, 2021·Toxicologic Pathology·Susan A ElmoreMichelle Cora

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Methods Mentioned

BETA
electron microscopy
transgenic

Software Mentioned

INHAND

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