PMID: 2107800Jan 1, 1990Paper

Nonsteroid anti-inflammatory drugs prevent the recurrence of heterotopic ossification after excision

Archives of Orthopaedic and Trauma Surgery
B SodemannO S Nilsson

Abstract

The prophylactic effect of nonsteroid anti-inflammatory drugs on the recurrence of high-grade periarticular heterotopic ossification after resection was studied in ten patients operated on for loosening of one or both components of a cemented total hip prosthesis. These drugs, given at a standard dosage for 1-3 weeks after surgery, prevented the recurrence of heterotopic ossification. In some patients the range of motion of their joint increased following surgery, while it remained unaffected in the majority. At follow-up 2-5 years after surgery, all patients walked well and there were no clinical or radiographs signs of loosening of the prosthetic components. It is concluded that treatment with NSAIDs following resection of periarticular heterotopic ossification prevents recurrence.

References

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Citations

Jan 7, 2010·Naunyn-Schmiedeberg's Archives of Pharmacology·Bertold RennerKay Brune
May 13, 1999·Current Opinion in Rheumatology·O S Nilsson, P E Persson
May 23, 2006·Journal of Hand Therapy : Official Journal of the American Society of Hand Therapists·Anne M Casavant, Hill Hastings
Jun 6, 2007·Hand Clinics·Douglas P HanelAndré Ayalla
May 1, 1997·Journal of Shoulder and Elbow Surgery·S L SummerfieldA P Weiss
Apr 21, 1999·Seminars in Radiation Oncology·S C FormentiP V Danenberg
Dec 1, 1991·The Proceedings of the Nutrition Society·R W Welch
Feb 8, 2000·Clinical Orthopaedics and Related Research·R W Viola, H Hastings
Jun 8, 2017·European Journal of Orthopaedic Surgery & Traumatology : Orthopédie Traumatologie·George A MacherasEleftherios Tsiridis
May 29, 1998·Acta Orthopaedica Scandinavica·O S Nilsson
Jan 12, 2001·Arthroscopy : the Journal of Arthroscopic & Related Surgery : Official Publication of the Arthroscopy Association of North America and the International Arthroscopy Association·W T Gofton, G J King
Mar 27, 1999·Seminars in Radiation Oncology·T C Lo

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