Abstract
There has been no study investigating nonsteroidal anti-inflammatory drugs (NSAIDs)-exacerbated respiratory disease (NERD) exclusively in childhood. Therefore, in the current study, the authors aimed to evaluate the diagnostic features, clinical characteristics, and follow-up of adolescents diagnosed with NERD. The patients who were consecutively diagnosed with NERD between January 2011, and November 2013, included in the study. Oral provocation test (OPT) with at least 2 different NSAIDs was used to confirm NSAID hypersensitivity in patients with underlying asthma/chronic rhinosinusitis/nasal polyps. All patients were followed regularly in 3-month intervals by the Pediatric Allergy and Otorhinolaryngology Department for asthma, allergic rhinitis, or chronic rhinosinusitis with or without nasal polyps. A total of 10 adolescents with NERD were included in the study. The mean age of the patients at the time of diagnosis was 14.9 ± 1.5 years. Hives or angioedema accompanied respiratory complaints induced by NSAIDs. The mean duration of follow-up was 28.9 ± 12.4 months. All patients had asthma except 1 with asymptomatic bronchial hyperreactivity. Asthma of patients was well-controlled with moderate dose of inhaled corticosteroids. ...Continue Reading
References
Oct 12, 2000·The European Respiratory Journal·A SzczeklikM Duplaga
Jan 18, 2003·The Journal of Allergy and Clinical Immunology·M Pilar Berges-GimenoDonald D Stevenson
Jun 30, 2005·Annals of Allergy, Asthma & Immunology : Official Publication of the American College of Allergy, Asthma, & Immunology·Kimberly MasciaJohn W Steinke
Nov 9, 2005·The Journal of Allergy and Clinical Immunology·Kimberly MasciaUNKNOWN TENOR Study Group
Jan 2, 2008·The European Respiratory Journal·E D BatemanH J Zar
Mar 26, 2008·Allergy·J BousquetUNKNOWN AllerGen
Jan 11, 2011·Allergy, Asthma & Immunology Research·Rachel U Lee, Donald D Stevenson
Apr 4, 2012·Rhinology·Wytske J FokkensPeter John Wormald
Sep 29, 2012·International Archives of Allergy and Immunology·Riccardo AseroMaria Josè Torres-Jaen
Oct 11, 2012·Seminars in Respiratory and Critical Care Medicine·Andrew A White, Donald D Stevenson
Nov 15, 2012·International Journal of Pediatric Otorhinolaryngology·Brian S ChenScott C Manning
Mar 20, 2013·Pediatric Allergy and Immunology : Official Publication of the European Society of Pediatric Allergy and Immunology·Maria A ZamboninoJose L Corzo
Jun 21, 2013·Paediatric Anaesthesia·Rohan AmeratungaBrian J Anderson
Sep 3, 2013·The Journal of Allergy and Clinical Immunology·Grazyna BochenekEwa Nizankowska-Mogilnicka
Oct 1, 2013·Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology·P AyusoJ A Cornejo-García
Oct 15, 2013·Allergy·M L KowalskiJ Makowska
Oct 15, 2013·Allergy·O YilmazI Turktas
Dec 29, 2013·The Journal of Allergy and Clinical Immunology·Katharine M Woessner, Andrew A White
Citations
May 12, 2015·International Forum of Allergy & Rhinology·Joseph Jacobs
Jul 10, 2016·The Journal of Allergy and Clinical Immunology. in Practice·Katherine L TuttleTanya M Laidlaw
Apr 26, 2018·Pediatric Allergy and Immunology : Official Publication of the European Society of Pediatric Allergy and Immunology·Mona KidonMarina Atanaskovic-Markovic
Sep 15, 2018·Allergy·Marek L KowalskiAleksandra Wardzyńska
Sep 9, 2018·Pediatric Allergy and Immunology : Official Publication of the European Society of Pediatric Allergy and Immunology·Ozlem CavkaytarDavide Caimmi
Aug 31, 2019·Pediatric Clinics of North America·Shazia Lutfeali, David A Khan