Nonsuppressible insulin-like activity (NSILA) from human serum: recent accomplishments and their physiologic implications
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Effects of insulin and NSILA on adipocytes of normal and diabetic rats: receptor binding, glucose transport and glucose metabolism
Studies of the biological activity of insulin, cyclic nucleotides and concanavalin A in the isolated fat cell
Insulin receptors in the heart muscle. Demonstration of specific binding sites and impairment of insulin binding in the plasma membrane of the obese hyperglycemic mouse
Circulating NSILA-s in man: Preliminary studies of stimuli in vivo and of binding to plasma components
Adrenocortical carcinoma and hypoglycemia: evidence for production of nonsuppressible insulin-like activity by the tumor
The influence of hypophysectomy on NSILA concentrations in the dog: evidence for partially pituitary-independent regulation
NSILA-carrier protein abolishes the action of nonsuppressible insulin-like activity (NSILA-S) on perfused rat heart
Insulin-like growth factors I and II: some biological actions and receptor binding characteristics of two purified constituents of nonsuppressible insulin-like activity of human serum
Estimation of somatomedin-C levels in normals and patients with pituitary disease by radioimmunoassay
Polypeptides with nonsuppressible insulin-like and cell-growth promoting activities in human serum: isolation, chemical characterization, and some biological properties of forms I and II
Nonsuppressible insulin-like activity and thyroid hormones: major pituitary-dependent sulfation factors for chick embryo cartilage
Amino-terminal sequences of two polypeptides from human serum with nonsuppressible insulin-like and cell-growth-promoting activities: evidence for structural homology with insulin B chain
Increased immunoreactive plasma and urinary growth hormone in growth retardation with defective generation of somatomedin a (Laron's Syndrome)
Insulin receptors in the liver: specific binding of ( 125 I)insulin to the plasma membrane and its relation to insulin bioactivity
DNA synthesis in human fibroblasts: stimulation by insulin and by nonsuppressible insulin-like activity (NSILA-S)
Effects of partially purified preparations with nonsuppressible insulin-like activity (NSILA-S) on sulfate incorporation into rat and chicken cartilage
Insulin-like activity by fat pad assay and immunoreactive insulin. II. Their occurrence in fractions by gel filtration of serum
Non-suppressible insulin-like activity of human serum. II. Biological properties of plasma extracts with non-suppressible insulin-like activity
ANTIBODY-SUPPRESSIBLE AND NONSUPPRESSIBLE INSULIN-LIKE ACTIVITIES IN HUMAN SERUM AND THEIR PHYSIOLOGIC SIGNIFICANCE. AN INSULIN ASSAY WITH ADIPOSE TISSUE OF INCREASED PRECISION AND SPECIFICITY
Regulation of insulin-like growth factor binding protein 4 by a specific insulin-like growth factor binding protein 4 proteinase in normal human osteoblast-like cells: implications in bone cell physiology
Mouse blastocysts respond metabolically to short-term stimulation by insulin and IGF-1 through the insulin receptor
The effect of acute and chronic insulin administration on insulin-like growth factor-I expression in the pituitary-intact and hypophysectomised rat
Evaluation of a radioimmunoassay for somatomedin-C/insulin-like growth factor I (Sm-C/IGF-I) in human plasma
The effect of insulin on intracellular ph and ribosomal protein S6 phosphorylation in oocytes of Xenopus laevis
Evidence for a biologically active, carrier-bound form of non-suppressible insulin-like activity (NSILA) in human serum
Recent advances in the biochemistry and physiology of the insulin-like growth factor/somatomedin family
Delay of puberty and impairment of growth in female rats given a non competitive antagonist of NMDA receptors
The occurrence of a distinct high molecular weight form of serum non-suppressible insulin-like activity
Induction of tyrosine aminotransferase and amino acid transport in rat hepatoma cells by insulin and the insulin-like growth factor, multiplication-stimulating activity. Mediation by insulin and multiplication-stimulating activity receptors
Stimulation of phospholipid synthesis in HeLa cells by epidermal growth factor and insulin: activation of choline kinase and glycerophosphate acyltransferase
Case records of the Massachusetts General Hospital. Weekly clinicopathological exercises. Case 5-1981
Sequential addition of platelet factor and plasma to BALB/c 3T3 fibroblast cultures stimulates somatomedin-C binding early in cell cycle
Stimulation of glucose incorporation and amino acid transport by insulin and an insulin-like growth factor in fibroblasts with defective insulin receptors cultured from a patient with leprechaunism
Sharing of biological effect and receptors between guinea pig insulin and platelet-derived growth factor
Insulin activates the appearance of insulin-like growth factor II receptors on the adipocyte cell surface
Production of monoclonal antibodies recognising different epitopes present on insulin-like growth factor 1
Inhibition of the action of nonsuppressible insulin-like activity on isolated rat fat cells by binding to its carrier protein
Direct demonstration of separate receptors for growth and metabolic activities of insulin and multiplication-stimulating activity (an insulinlike growth factor) using antibodies to the insulin receptor
Receptors for insulinlike growth factor I are defective in fibroblasts cultured from a patient with leprechaunism
Dual regulation of glycogen metabolism by insulin and insulin-like growth factors in human hepatoma cells (HEP-G2). Analysis with an anti-receptor monoclonal antibody
Human fetal and adult chondrocytes. Effect of insulinlike growth factors I and II, insulin, and growth hormone on clonal growth
Structural and functional characterization of the human T lymphocyte receptor for insulin-like growth factor I in vitro
Nonsuppressible insulin-like activity and somatomedin C levels in normal pregnant women, in pregnant women with gestational diabetes, and in umbilical cord blood of mature and premature infants
Receptors for insulin-like growth factors in rabbit articular and growth plate chondrocytes in culture
Structural differences between insulin and somatomedin-C/insulin-like growth factor-1 receptors revealed by autoantibodies to the insulin receptor
Receptors for insulin-like growth factor-I (IGF-I) in myocardial capillary endothelium of the intact perfused heart
A somatomedin-like peptide hormone is required during the estrogen-mediated induction of ovalbumin gene transcription
Insulin does not play the major role in the refeeding stimulation of hepatic ornithine decarboxylase activity
Variability among five different commercial IGF-1 immunoassays in conditions of childhood-onset GH deficiency and GH therapy
The use of a commercially available somatomedin-C radioimmunoassay in patients with disorders of growth
Production of insulin-like growth factors and their carrier by rat pituitary gland and brain explants in culture
Ovarian response to combined growth hormone-gonadotropin treatment in patients resistant to induction of superovulation
Insulin stimulates cord blood erythroid progenitor growth: evidence for an aetiological role in neonatal polycythaemia
Structural similarities between human receptors for somatomedin C and insulin: analysis by affinity labeling
Functional properties of an isolated alpha beta heterodimeric human placenta insulin-like growth factor 1 receptor complex
Multiplication stimulating activity (MSA) from the BRL 3A rat liver cell line: relation to human somatomedins and insulin
Complementation for the growth response to insulin and MSA occurs at a step distal to hormone-receptor interaction in mouse embryo fibroblast X melanoma cell hybrids
Variables controlling the secretion of a somatomedin-like peptide by cultured porcine smooth muscle cells
Mediation of the actions of insulin and insulin-like growth factor-1 on preimplantation mouse embryos in vitro
Endocrine influences on serum acid-ethanol soluble non-suppressible in insulin-like activity (NSILA-S)
Articular cartilage destruction in experimental inflammatory arthritis: insulin-like growth factor-1 regulation of proteoglycan metabolism in chondrocytes
Abnormalities of IGF-I signaling in the pathogenesis of diseases of the bone, brain, and fetoplacental unit in humans
Evidence for the synthesis of a somatomedin similar to insulin-like growth factor I by chick embryo liver cells
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