PMID: 2508004Sep 1, 1989Paper

Nonsurgical treatment of aggressive fibromatosis in the head and neck

Otolaryngology--head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery
C B WestM J Mansfield

Abstract

Aggressive fibromatosis is a poorly defined, locally aggressive, yet histologically benign fibroblastic proliferative lesion that may occur in the head and neck. The lesion is highly cellular and locally infiltrative and has a propensity to invade and erode bone, compromising vital structures within the head and neck. However, it is not a true malignancy because it does not have malignant cytologic characteristics nor does it metastasize. We present two cases of aggressive fibromatosis occurring in young adult men. The first case involved a rapidly enlarging mass of the anterior maxilla that involved the upper lip, nasal alae, nasal septum, inferior turbinates, and hard palate. The patient underwent incisional biopsy to confirm the diagnosis. Because of difficulty in determining the actual margins of this extensive lesion and the significant morbidity that would have resulted from surgical resection, we elected to treat this patient with chemotherapy and radiation therapy. The second case was an extensive lesion involving the right temporal bone, pterygomaxillary space, and infratemporal, temporal, and middle cranial fossae. Incisional biopsy confirmed the diagnosis. Because of the lack of functional and cosmetic deficits and t...Continue Reading

References

Mar 1, 1977·The Journal of Pediatrics·R Stein
Aug 1, 1975·Cancer·H D Suit, W O Russell
Oct 11, 1975·American Journal of Surgery·S A WilkinsC A Droulias
Apr 1, 1985·The Journal of Laryngology and Otology·K Kwong
Jan 1, 1973·The American Journal of Roentgenology, Radium Therapy, and Nuclear Medicine·D R HillT L Phillips
Jul 1, 1969·Annals of Surgery·T K Das GuptaJ O'Hara
Oct 1, 1966·American Journal of Surgery·J ConleyA P Stout
Oct 1, 1966·American Journal of Surgery·J K Masson, E H Soule
Oct 1, 1984·British Journal of Plastic Surgery·S J Siemssen, T Anagnostaki
Aug 1, 1983·International Journal of Radiation Oncology, Biology, Physics·S A LeibelT L Phillips
Mar 1, 1981·International Journal of Radiation Oncology, Biology, Physics·H M GreenbergJ R Cassady

❮ Previous
Next ❯

Citations

Apr 1, 1995·Clinical Otolaryngology and Allied Sciences·B E PlaatR B Keus
Aug 19, 2006·Arquivos de neuro-psiquiatria·Oswaldo Inácio de TellaCelso Agner
Jan 15, 2014·Head & Neck·Eelco de BreeRemco de Bree
Aug 30, 2000·Otolaryngology--head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery·N S Siegel, C R Bradford
May 1, 1992·The Journal of Laryngology and Otology·Y el-Sayed
Dec 1, 1993·Cancer·S R PatelR S Benjamin
Sep 6, 2005·Mund-, Kiefer- und Gesichtschirurgie : MKG·L SeperJ Kleinheinz
Nov 5, 1998·Neurosurgery·M J Perez-CruetF DeMonte
Nov 25, 2003·Neuroimaging Clinics of North America·Paul A CarusoAlfred L Weber
Sep 10, 2008·Journal of Pediatric Surgery·Alok SharmaVito Forte

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Case Reports in Oncological Medicine
Ahmed Abu-ZaidTarek Amin
Gynécologie, obstétrique & fertilité
S CroceC Mathelin
The Annals of Otology, Rhinology, and Laryngology
W T MoriokaR W Cantrell
© 2022 Meta ULC. All rights reserved