journal cover

Nontoxic amphiphilic carbon dots as promising drug nanocarriers across the blood-brain barrier and inhibitors of β-amyloid

Nanoscale

Nov 15, 2019

Yi-qun ZhouRoger M Leblanc

Get paper from

Abstract

The blood-brain barrier (BBB) is a main obstacle for drug delivery targeting the central nervous system (CNS) and treating Alzheimer's disease (AD). In order to enhance the efficiency of drug delivery without harming the BBB integrity, nanoparticle-mediated drug delivery has become a po...read more

Mentioned in this Paper

Alzheimer's Disease
Blood - Brain Barrier Anatomy
Brain
Cadmium
Carbon
Drug Carriers
Pathology
Zebrafish
1,2-diaminobenzene
Citric Acid
2
1
3
Paper Details
References
  • References42
  • Citations
12345
  • References42
  • Citations
  • quote and clock

    No citations available

    This paper may not have been cited yet.

Similar Papers Found In These Feeds

Drug Delivery & Bio-Conjugation

This feed describes how bioconjugation, a covalent linking between the drug molecule and a biomolecule, can alter (facilitate or impede) drug delivery in living organisms. Discover the latest research on bioconjugation in drug delivery here

Blood Brain Barrier

The blood brain barrier is a border that separates blood from cerebrospinal fluid. Discover the latest search on this highly selective semipermeable membrane here.

Gut Microbiome & the Brain

Microbes in the gut communicate with the central nervous system (CNS) via at least three parallel and interacting channels including endocrine, nervous, and immune signaling. Here is the latest research on the brain-gut-microbiome axis.

Alzheimer's Disease: Abeta

Alzheimer's disease (AD) is a chronic neurodegenerative disease associated with accumulation of amyloid plaques, which are comprised of amyloid beta. Here is the latest research in this field.

Blood Brain Barrier Chips

The blood brain barrier (BBB) is comprised of endothelial cells that regulate the influx and outflux of plasma concentrations. Lab-on-a-chip devices allow scientists to model diseases and mechanisms such as the passage of therapeutic antibodies across the BBB. Discover the latest research on BBB chips here.

Alzheimer's Disease: APP

Amyloid precursor protein proteolysis is critical for the development of Alzheimer's disease, a neurodegenerative disease associated with accumulation of amyloid plaques. Here is the latest research.

© 2019 Meta ULC. All rights reserved

Nontoxic amphiphilic carbon dots as promising drug nanocarriers across the blood-brain barrier and inhibitors of β-amyloid

Nanoscale

Nov 15, 2019

Yi-qun ZhouRoger M Leblanc

PMID: 31730144

DOI: 10.1039/c9nr08194a

Abstract

The blood-brain barrier (BBB) is a main obstacle for drug delivery targeting the central nervous system (CNS) and treating Alzheimer's disease (AD). In order to enhance the efficiency of drug delivery without harming the BBB integrity, nanoparticle-mediated drug delivery has become a po...read more

Mentioned in this Paper

Alzheimer's Disease
Blood - Brain Barrier Anatomy
Brain
Cadmium
Carbon
2
1
3

Similar Papers Found In These Feeds

Related Papers

Paper Details
References
  • References42
  • Citations
12345
  • References42
  • Citations
  • quote and clock

    No citations available

    This paper may not have been cited yet.

Get paper from

/papers/nontoxic-amphiphilic-carbon-dots-as-promising/31730144